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Cellosaurus HNE-1 (CVCL_0308)

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Cell line name HNE-1
Synonyms HNE1
Accession CVCL_0308
Resource Identification Initiative To cite this cell line use: HNE-1 (RRID:CVCL_0308)
Comments Problematic cell line: Possibly contaminated. The STR profile is very similar to that of the HeLa cell line and almost identical to that of HNE-2 (Cellosaurus=CVCL_FA07).
Virology: EBV-negative in established line.
Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Omics: Transcriptomics; RNAseq.
Disease Nasopharyngeal carcinoma (NCIt: C3871)
Nasopharyngeal carcinoma (ORDO: Orphanet_150)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=18196576; PubMed=25877200

Markers:
AmelogeninX
CSF1PO10,11
D2S133817,23
D3S135815,18
D5S81811,12
D7S82010,12
D8S117912,16 (PubMed=18196576)
12,17 (PubMed=25877200)
D13S31710,12,13.3
D16S5399,10 (PubMed=18196576)
9,10,11 (PubMed=25877200)
D18S5113,16
D19S43313
D21S1127,30
FGA18,21
Penta D9,12
Penta E17,20
TH016,7,9 (PubMed=18196576)
6,9 (PubMed=25877200)
TPOX8,12
vWA14,16

Run an STR similarity search on this cell line
Publications

PubMed=2556716; DOI=10.1073/pnas.86.23.9524; PMCID=PMC298529
Ronald Glaser, Hai-Ying Zhang, Kai-Tai Yao, He-Cheng Zhu, Fu-Xi Wang, Gui-Yuan Li, Dong-Seng Wen, Ying-Ping Li;
Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected with Epstein-Barr virus that were derived from nasopharyngeal carcinomas.
Proc. Natl. Acad. Sci. U.S.A. 86:9524-9528(1989)

PubMed=18196576; DOI=10.1002/ijc.23374
Sylvia Yat-Yee Chan, Kwong-Wai Choy, George Sai-Wah Tsao, Qian Tao, Tao Tang, Grace Tin-Yun Chung, Kwok-Wai Lo;
Authentication of nasopharyngeal carcinoma tumor lines.
Int. J. Cancer 122:2169-2171(2008)

PubMed=25877200; DOI=10.1038/nature14397
Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve;
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

CLPUB00484
Zhi-Hong Xu, Wen-Wen Sun, Jun-Biao Hang, Bei-Li Gao, Jia-An Hu;
RNA-seq identified a novel functional MET fusion in head and neck cancer 5-8F cell line.
Int. J. Clin. Exp. Pathol. 9:8308-8317(2016)

Cross-references
Cell line databases/resources MCCL; MCC:0000201
Anatomy/cell type resources BTO; BTO_0006135
Biological sample resources BioSample; SAMN03472440
Encyclopedic resources Wikidata; Q54890030
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number21