ID   HNE-1
AC   CVCL_0308
SY   HNE1
DR   BTO; BTO:0006135
DR   MCCL; MCC:0000201
DR   BioSample; SAMN03472440
DR   Wikidata; Q54890030
RX   CelloPub=CLPUB00484;
RX   PubMed=2556716;
RX   PubMed=18196576;
RX   PubMed=25877200;
CC   Problematic cell line: Possibly contaminated. The STR profile is very similar to that of the HeLa cell line and almost identical to that of HNE-2 (Cellosaurus=CVCL_FA07).
CC   Virology: EBV-negative in established line.
CC   Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
CC   Omics: Transcriptome analysis by RNAseq.
ST   Source(s): PubMed=18196576; PubMed=25877200
ST   Amelogenin: X
ST   CSF1PO: 10,11
ST   D13S317: 10,12,13.3
ST   D16S539: 9,10 (PubMed=18196576)
ST   D16S539: 9,10,11 (PubMed=25877200)
ST   D18S51: 13,16
ST   D19S433: 13
ST   D21S11: 27,30
ST   D2S1338: 17,23
ST   D3S1358: 15,18
ST   D5S818: 11,12
ST   D7S820: 10,12
ST   D8S1179: 12,16 (PubMed=18196576)
ST   D8S1179: 12,17 (PubMed=25877200)
ST   FGA: 18,21
ST   Penta D: 9,12
ST   Penta E: 17,20
ST   TH01: 6,7,9 (PubMed=18196576)
ST   TH01: 6,9 (PubMed=25877200)
ST   TPOX: 8,12
ST   vWA: 14,16
DI   NCIt; C3871; Nasopharyngeal carcinoma
DI   ORDO; Orphanet_150; Nasopharyngeal carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 19
//
RX   CelloPub=CLPUB00484;
RA   Xu Z.-H., Sun W.-W., Hang J.-B., Gao B.-L., Hu J.-A.;
RT   "RNA-seq identified a novel functional MET fusion in head and neck
RT   cancer 5-8F cell line.";
RL   Int. J. Clin. Exp. Pathol. 9:8308-8317(2016).
//
RX   PubMed=2556716; DOI=10.1073/pnas.86.23.9524;
RA   Glaser R., Zhang H.-Y., Yao K.-T., Zhu H.-C., Wang F.-X., Li G.-Y.,
RA   Wen D.-S., Li Y.-P.;
RT   "Two epithelial tumor cell lines (HNE-1 and HONE-1) latently infected
RT   with Epstein-Barr virus that were derived from nasopharyngeal
RT   carcinomas.";
RL   Proc. Natl. Acad. Sci. U.S.A. 86:9524-9528(1989).
//
RX   PubMed=18196576; DOI=10.1002/ijc.23374;
RA   Chan S.Y.-Y., Choy K.-W., Tsao S.-W., Tao Q., Tang T., Chung G.T.-Y.,
RA   Lo K.-W.;
RT   "Authentication of nasopharyngeal carcinoma tumor lines.";
RL   Int. J. Cancer 122:2169-2171(2008).
//
RX   PubMed=25877200; DOI=10.1038/nature14397;
RA   Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M.,
RA   Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S.,
RA   Neve R.M.;
RT   "A resource for cell line authentication, annotation and quality
RT   control.";
RL   Nature 520:307-311(2015).
//