Cellosaurus cell line HIB 1B (CVCL

Cellosaurus HIB 1B (CVCL_0299)

Cross-references
Cell line name	HIB 1B
Synonyms	HIB-1B; HIB1B
Accession	CVCL_0299
Resource Identification Initiative	To cite this cell line use: HIB 1B (RRID:CVCL_0299)
Comments	Characteristics: Expresses UCP. Differentiates into adipocyte-like cells (PubMed=1323843). Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen. Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40). Derived from site: In situ; Brown adipose tissue; UBERON=UBERON_0001348. Cell type: Preadipocyte; CL=CL_0002334.
Disease	Mouse hibernoma (NCIt: C21634)
Species of origin	Mus musculus (Mouse) (NCBI Taxonomy: 10090) Breed/subspecies: aP2-TAg transgenic.
Sex of cell	Male
Age at sampling	Age unspecified
Category	Transformed cell line
Web pages	Info; Wikipedia; -; https://ca.wikipedia.org/wiki/C%C3%A8l%C2%B7lules_HIB_1B
Publications	PubMed=1323843; DOI=10.1073/pnas.89.16.7561; PMCID=PMC49750 Susan R. Ross, Lisa Choy, Reed A. Graves, Niles Fox, Veronica Solevjeva, Susanne Klaus, Daniel Ricquier, Bruce Michael Spiegelman; Hibernoma formation in transgenic mice and isolation of a brown adipocyte cell line expressing the uncoupling protein gene. Proc. Natl. Acad. Sci. U.S.A. 89:7561-7565(1992) PubMed=8175918; DOI=10.1242/jcs.107.1.313 Susanne Klaus, Lisa Choy, Odette Champigny, Anne-Marie Cassard-Doulcier, Susan R. Ross, Bruce Michael Spiegelman, Daniel Ricquier; Characterization of the novel brown adipocyte cell line HIB 1B Adrenergic pathways involved in regulation of uncoupling protein gene expression. J. Cell Sci. 107:313-319(1994)
Cell line databases/resources	MCCL; MCC:0000190 Lonza; 279
Anatomy/cell type resources	BTO; BTO_0005964
Encyclopedic resources	Wikidata; Q54889533
Experimental variables resources	EFO; EFO_0022808
Entry history
Entry creation	04-Apr-2012
Last entry update	14-Aug-2025
Version number	14