ID   HIB 1B
AC   CVCL_0299
SY   HIB-1B; HIB1B
DR   BTO; BTO_0005964
DR   EFO; EFO_0022808
DR   MCCL; MCC:0000190
DR   Lonza; 279
DR   Wikidata; Q54889533
RX   PubMed=1323843;
RX   PubMed=8175918;
WW   Info; Wikipedia; -; https://ca.wikipedia.org/wiki/C%C3%A8l%C2%B7lules_HIB_1B
CC   Characteristics: Expresses UCP. Differentiates into adipocyte-like cells (PubMed=1323843).
CC   Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
CC   Derived from site: In situ; Brown adipose tissue; UBERON=UBERON_0001348.
CC   Cell type: Preadipocyte; CL=CL_0002334.
CC   Breed/subspecies: aP2-TAg transgenic.
DI   NCIt; C21634; Mouse hibernoma
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Male
AG   Age unspecified
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 13
//
RX   PubMed=1323843; DOI=10.1073/pnas.89.16.7561; PMCID=PMC49750;
RA   Ross S.R., Choy L., Graves R.A., Fox N., Solevjeva V., Klaus S.,
RA   Ricquier D., Spiegelman B.M.;
RT   "Hibernoma formation in transgenic mice and isolation of a brown
RT   adipocyte cell line expressing the uncoupling protein gene.";
RL   Proc. Natl. Acad. Sci. U.S.A. 89:7561-7565(1992).
//
RX   PubMed=8175918; DOI=10.1242/jcs.107.1.313;
RA   Klaus S., Choy L., Champigny O., Cassard-Doulcier A.-M., Ross S.R.,
RA   Spiegelman B.M., Ricquier D.;
RT   "Characterization of the novel brown adipocyte cell line HIB 1B.
RT   Adrenergic pathways involved in regulation of uncoupling protein gene
RT   expression.";
RL   J. Cell Sci. 107:313-319(1994).
//