Cellosaurus logo
expasy logo

Cellosaurus H9c2(2-1) (CVCL_0286)

[Text][XML][JSON]
Cell line name H9c2(2-1)
Synonyms H9c2 (2-1); H9c2; H9C2
Accession CVCL_0286
Resource Identification Initiative To cite this cell line use: H9c2(2-1) (RRID:CVCL_0286)
Comments Derived from site: In situ; Embryonic heart, cardiac muscle; UBERON=UBERON_0003084+UBERON_0001133.
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: BDIX; RS=RS_0000091.
Hierarchy Children:
CVCL_B0FS (H9c2 Trpm4 KO)CVCL_C8V4 (H9C2(2-1)-Luc)CVCL_XE64 (H9C2(2-1)-Luc2-tdT)
CVCL_XE65 (H9C2(2-1)-mCherry)CVCL_XE66 (H9C2(2-1)-tdT)CVCL_E1JX (HyCyte H9c2(2-1) KO-rCpt1a)
CVCL_F1NZ (HyCyte H9c2(2-1) KO-rLOC102549962)CVCL_E1JY (HyCyte H9c2(2-1) KO-rMapk1)CVCL_D8GF (Ubigene H9c2(2-1) Ankrd23 KO)
CVCL_D8GG (Ubigene H9c2(2-1) Dsp KO)CVCL_D8GH (Ubigene H9c2(2-1) Fgfr1 KO)CVCL_D8GI (Ubigene H9c2(2-1) Glp1r KO)
CVCL_D8GJ (Ubigene H9c2(2-1) Hif1an KO)CVCL_D8GK (Ubigene H9c2(2-1) Otub1 KO)CVCL_D8GL (Ubigene H9c2(2-1) Piezo2 KO)
CVCL_D8GM (Ubigene H9c2(2-1) Scaf1 KO)CVCL_D8GN (Ubigene H9c2(2-1) Senp1 KO)CVCL_D8GP (Ubigene H9c2(2-1) Tmem175 KO)
CVCL_D8GQ (Ubigene H9c2(2-1) Tpm1 KO)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Spontaneously immortalized cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/h/cell-lines-detail-409.html
Publications

PubMed=943302; DOI=10.1016/0014-4827(76)90447-X
Brian W. Kimes, Bruce L. Brandt;
Properties of a clonal muscle cell line from rat heart.
Exp. Cell Res. 98:367-381(1976)

PubMed=1683272; DOI=10.1161/01.RES.69.6.1476
Jurgen Hescheler, Rainer Meyer, Sabine Plant, Dietmar Krautwurst, Walter Rosenthal, Gunter Schultz;
Morphological, biochemical, and electrophysiological characterization of a clonal cell (H9c2) line from rat heart.
Circ. Res. 69:1476-1486(1991)

PubMed=17662623; DOI=10.1016/j.vascn.2007.06.001
Beshay Nazmy Mounir Zordoky, Ayman O.S. El-Kadi;
H9c2 cell line is a valuable in vitro model to study the drug metabolizing enzymes in the heart.
J. Pharmacol. Toxicol. Methods 56:317-322(2007)

PubMed=21082279; DOI=10.1007/s11626-010-9368-1
Sarah J. Watkins, Gillian M. Borthwick, Helen M. Arthur;
The H9C2 cell line and primary neonatal cardiomyocyte cells show similar hypertrophic responses in vitro.
In Vitro Cell. Dev. Biol. Anim. 47:125-131(2011)

Cross-references
Cell line collections (Providers) AddexBio; C0031002/5017
ATCC; CRL-1446
BCRC; 60096
BCRJ; 0098
CCTCC; GDC0606
CLS; 305203
ECACC; 88092904
IZSLER; BS CL 151
KCLB; 21446
NCBI_Iran; C585
Ubigene; YC-A009
Cell line databases/resources CLO; CLO_0003614
MCCL; MCC:0000176
CLDB; cl1558
CLDB; cl5196
CCRID; 1101RAT-PUMC000219
CCRID; 3101RATGNR5
CCRID; 4201RAT-CCTCC00606
Lonza; 1016
Anatomy/cell type resources BTO; BTO_0001879
Chemistry resources ChEMBL-Cells; CHEMBL3307653
ChEMBL-Targets; CHEMBL614576
PubChem_Cell_line; CVCL_0286
Encyclopedic resources Wikidata; Q9363821
Gene expression databases GEO; GSM1513690
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number30