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Cellosaurus GH3 (CVCL_0273)

[Text version]
Cell line name GH3
Synonyms GH 3
Accession CVCL_0273
Resource Identification Initiative To cite this cell line use: GH3 (RRID:CVCL_0273)
Comments Doubling time: ~60-90 hours (DSMZ=ACC-469).
Derived from site: In situ; Pituitary gland; UBERON=UBERON_0000007.
Disease Rat pituitary gland neoplasm (NCIt: C132194)
Species of origin Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: Wistar Furth; RS=RS_0000982.
Hierarchy Children:
CVCL_U370 (GH3/GH-EYFP)CVCL_0274 (GH3B6)CVCL_UJ46 (GH3C1)
CVCL_UJ47 (GH3C6)CVCL_0276 (GH4C1)
Originate from same individual CVCL_0610 ! GH1
Sex of cell Female
Age at sampling 7M
Category Cancer cell line
Web pages Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/g/cell-lines-detail-288.html
Publications

PubMed=4951281; DOI=10.1210/endo-82-2-342
Armen Haig Tashjian Jr., Yosihiro Yasumura, Lawrence Levine, Gordon Hisashi Sato, Mary L. Parker;
Establishment of clonal strains of rat pituitary tumor cells that secrete growth hormone.
Endocrinology 82:342-352(1968)

PubMed=5513559; DOI=10.1083/jcb.47.1.61; PMCID=PMC2108385
Armen Haig Tashjian Jr., Frank Carter Bancroft, Lawrence Levine;
Production of both prolactin and growth hormone by clonal strains of rat pituitary tumor cells. Differential effects of hydrocortisone and tissue extracts.
J. Cell Biol. 47:61-70(1970)

PubMed=4327442; DOI=10.1016/0006-291X(71)90644-9
Armen Haig Tashjian Jr., Norma J. Barowsky, Diane K. Jensen;
Thyrotropin releasing hormone: direct evidence for stimulation of prolactin production by pituitary cells in culture.
Biochem. Biophys. Res. Commun. 43:516-523(1971)

PubMed=218079; DOI=10.1016/S0076-6879(79)58167-1
Armen Haig Tashjian Jr.;
Clonal strains of hormone-producing pituitary cells.
Methods Enzymol. 58:527-535(1979)

PubMed=15541569; DOI=10.1016/j.mce.2004.07.018
Guck T. Ooi, Neveen Tawadros, Ruth M. Escalona;
Pituitary cell lines and their endocrine applications.
Mol. Cell. Endocrinol. 228:1-21(2004)

Cross-references
Cell line collections (Providers) ATCC; CCL-82.1
BCRC; 60015
BCRJ; 0090
CLS; 300383
DSMZ; ACC-469
ECACC; 87012603
ICLC; ATL96003
IZSLER; BS TCL 18
JCRB; IFO50105
JCRB; JCRB9047
KCLB; 10082.1
Cell line databases/resources CLO; CLO_0003482
CLO; CLO_0003484
CLO; CLO_0003487
MCCL; MCC:0000164
CLDB; cl1455
CLDB; cl1456
CLDB; cl1457
CLDB; cl1458
CCRID; 1101RAT-PUMC000008
DSMZCellDive; ACC-469
Lonza; 613
TOKU-E; 1327
Anatomy/cell type resources BTO; BTO_0001410
Chemistry resources ChEMBL-Cells; CHEMBL3307652
ChEMBL-Targets; CHEMBL614571
PubChem_Cell_line; CVCL_0273
Encyclopedic resources Wikidata; Q54835769
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number28