ID   GH3
AC   CVCL_0273
SY   GH 3
DR   BTO; BTO_0001410
DR   CLO; CLO_0003482
DR   CLO; CLO_0003484
DR   CLO; CLO_0003487
DR   MCCL; MCC:0000164
DR   CLDB; cl1455
DR   CLDB; cl1456
DR   CLDB; cl1457
DR   CLDB; cl1458
DR   ATCC; CCL-82.1
DR   BCRC; 60015
DR   BCRJ; 0090
DR   CCRID; 1101RAT-PUMC000008
DR   ChEMBL-Cells; CHEMBL3307652
DR   ChEMBL-Targets; CHEMBL614571
DR   CLS; 300383
DR   DSMZ; ACC-469
DR   DSMZCellDive; ACC-469
DR   ECACC; 87012603
DR   ICLC; ATL96003
DR   IZSLER; BS TCL 18
DR   JCRB; IFO50105
DR   JCRB; JCRB9047
DR   KCLB; 10082.1
DR   Lonza; 613
DR   PubChem_Cell_line; CVCL_0273
DR   TOKU-E; 1327
DR   Wikidata; Q54835769
RX   PubMed=218079;
RX   PubMed=4327442;
RX   PubMed=4951281;
RX   PubMed=5513559;
RX   PubMed=15541569;
WW   Info; Thermo Fisher; -; https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/g/cell-lines-detail-288.html
CC   Doubling time: ~60-90 hours (DSMZ=ACC-469).
CC   Derived from site: In situ; Pituitary gland; UBERON=UBERON_0000007.
CC   Breed/subspecies: Wistar Furth; RS=RS_0000982.
DI   NCIt; C132194; Rat pituitary gland neoplasm
OX   NCBI_TaxID=10116; ! Rattus norvegicus (Rat)
OI   CVCL_0610 ! GH1
SX   Female
AG   7M
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 28
CH   CVCL_F0SI ! GH3-ha7-22
CH   CVCL_U370 ! GH3/GH-EYFP
CH   CVCL_0274 ! GH3B6
CH   CVCL_UJ46 ! GH3C1
CH   CVCL_UJ47 ! GH3C6
CH   CVCL_0276 ! GH4C1
//
RX   PubMed=4327442; DOI=10.1016/0006-291X(71)90644-9;
RA   Tashjian, Armen Haig Jr.
RA   Barowsky, Norma J.
RA   Jensen, Diane K.
RT   "Thyrotropin releasing hormone: direct evidence for stimulation of
RT   prolactin production by pituitary cells in culture.";
RL   Biochem. Biophys. Res. Commun. 43:516-523(1971).
//
RX   PubMed=4951281; DOI=10.1210/endo-82-2-342;
RA   Tashjian, Armen Haig Jr.
RA   Yasumura, Yosihiro
RA   Levine, Lawrence
RA   Sato, Gordon Hisashi
RA   Parker, Mary L.
RT   "Establishment of clonal strains of rat pituitary tumor cells that
RT   secrete growth hormone.";
RL   Endocrinology 82:342-352(1968).
//
RX   PubMed=15541569; DOI=10.1016/j.mce.2004.07.018;
RA   Ooi, Guck T.
RA   Tawadros, Neveen
RA   Escalona, Ruth M.
RT   "Pituitary cell lines and their endocrine applications.";
RL   Mol. Cell. Endocrinol. 228:1-21(2004).
//
RX   PubMed=5513559; DOI=10.1083/jcb.47.1.61; PMCID=PMC2108385;
RA   Tashjian, Armen Haig Jr.
RA   Bancroft, Frank Carter
RA   Levine, Lawrence
RT   "Production of both prolactin and growth hormone by clonal strains of
RT   rat pituitary tumor cells. Differential effects of hydrocortisone and
RT   tissue extracts.";
RL   J. Cell Biol. 47:61-70(1970).
//
RX   PubMed=218079; DOI=10.1016/S0076-6879(79)58167-1;
RA   Tashjian, Armen Haig Jr.
RT   "Clonal strains of hormone-producing pituitary cells.";
RL   Methods Enzymol. 58:527-535(1979).
//