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Cellosaurus D10G41 (CVCL_0241)

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Cell line name D10G41
Synonyms D10.G4.1; D10
Accession CVCL_0241
Resource Identification Initiative To cite this cell line use: D10G41 (RRID:CVCL_0241)
Comments Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
Characteristics: IL1A or IL1B dependent.
Characteristics: Used extensively to study activation of T-cells (ATCC=TIB-224).
Doubling time: ~30 hours (DSMZ=ACC-45).
Derived from site: In situ; Lymph node; UBERON=UBERON_0000029.
Cell type: CD4-positive helper T cell; CL=CL_0000492.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: AKR/J.
Hierarchy Children:
CVCL_HE72 (D10S)
Sex of cell Male
Age at sampling Adult
Category Factor-dependent cell line
STR profile Source(s): PubMed=31220119

Markers:
Mouse STR 1-114
Mouse STR 1-212,13
Mouse STR 2-19
Mouse STR 3-210
Mouse STR 4-219.3,20.3
Mouse STR 5-511
Mouse STR 6-417,18,19
Mouse STR 6-716,17
Mouse STR 7-125.2
Mouse STR 8-116
Mouse STR 11-216,17,18,19
Mouse STR 12-116
Mouse STR 13-114,15
Mouse STR 15-320.3
Mouse STR 17-216
Mouse STR 18-316,17,18
Mouse STR 19-212
Mouse STR X-126

Run an STR similarity search on this cell line
Publications

PubMed=6193236; DOI=10.1084/jem.158.3.836; PMCID=PMC2187090
Jonathan Kaye, Steven Anthony Porcelli, John Philip Tite, Barry Jones, Charles Alderson Janeway Jr.;
Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells.
J. Exp. Med. 158:836-856(1983)

PubMed=2953804; DOI=10.4049/jimmunol.138.12.4288
Thomas Seth Kupper, Patrick Flood, David Coleman, Mark Horowitz;
Growth of an interleukin 2/interleukin 4-dependent T cell line induced by granulocyte-macrophage colony-stimulating factor (GM-CSF).
J. Immunol. 138:4288-4292(1987)

PubMed=31220119; DOI=10.1371/journal.pone.0218412; PMCID=PMC6586308
Jamie L. Almeida, Aleksandra Dakic, Karin Kindig, Maikan Kone, Deborah Lee Dormady Letham, Scott Langdon, Ruth Peat, Jayamalini Holding-Pillai, Erin M. Hall, Mark Ladd, Megan D. Shaffer ...Show all 23 authors... , Heath Berg, Jin-Liang Li, Georges Wigger, Steve Lund, Carolyn R. Steffen, Barbara B. Fransway, Bob Geraghty, Manuela Natoli, Beth A. Bauer, Susanne M. Gollin, Dale W. Lewis, Yvonne A. Reid; Show fewer authors
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:e0218412.1-e0218412.24(2019)

Cross-references
Cell line collections (Providers) ATCC; TIB-224
DSMZ; ACC-45
Cell line databases/resources CLO; CLO_0002659
MCCL; MCC:0000131
CLDB; cl969
DSMZCellDive; ACC-45
Biological sample resources BioSample; SAMN11397660
Encyclopedic resources Wikidata; Q54817163
Experimental variables resources EFO; EFO_0002822
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number17