ID   D10G41
AC   CVCL_0241
SY   D10.G4.1; D10
DR   CLO; CLO_0002659
DR   EFO; EFO_0002822
DR   MCCL; MCC:0000131
DR   CLDB; cl969
DR   ATCC; TIB-224
DR   BioSample; SAMN11397660
DR   DSMZ; ACC-45
DR   DSMZCellDive; ACC-45
DR   Wikidata; Q54817163
RX   PubMed=2953804;
RX   PubMed=6193236;
RX   PubMed=31220119;
CC   Part of: Tumor Immunology Bank (TIB) collection from Salk (transferred to ATCC in 1981).
CC   Characteristics: IL1A or IL1B dependent.
CC   Characteristics: Used extensively to study activation of T-cells (ATCC=TIB-224).
CC   Doubling time: ~30 hours (DSMZ=ACC-45).
CC   Derived from site: In situ; Lymph node; UBERON=UBERON_0000027.
CC   Cell type: CD4-positive helper T cell; CL=CL_0000492.
CC   Breed/subspecies: AKR/J.
ST   Source(s): PubMed=31220119
ST   Mouse STR 1-1: 14
ST   Mouse STR 1-2: 12,13
ST   Mouse STR 11-2: 16,17,18,19
ST   Mouse STR 12-1: 16
ST   Mouse STR 13-1: 14,15
ST   Mouse STR 15-3: 20.3
ST   Mouse STR 17-2: 16
ST   Mouse STR 18-3: 16,17,18
ST   Mouse STR 19-2: 12
ST   Mouse STR 2-1: 9
ST   Mouse STR 3-2: 10
ST   Mouse STR 4-2: 19.3,20.3
ST   Mouse STR 5-5: 11
ST   Mouse STR 6-4: 17,18,19
ST   Mouse STR 6-7: 16,17
ST   Mouse STR 7-1: 25.2
ST   Mouse STR 8-1: 16
ST   Mouse STR X-1: 26
OX   NCBI_TaxID=10090; ! Mus musculus (Mouse)
SX   Male
AG   Adult
CA   Factor-dependent cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 15
//
RX   PubMed=2953804; DOI=10.4049/jimmunol.138.12.4288;
RA   Kupper T.S., Flood P., Coleman D., Horowitz M.;
RT   "Growth of an interleukin 2/interleukin 4-dependent T cell line
RT   induced by granulocyte-macrophage colony-stimulating factor (GM-CSF).";
RL   J. Immunol. 138:4288-4292(1987).
//
RX   PubMed=6193236; DOI=10.1084/jem.158.3.836;
RA   Kaye J., Porcelli S.A., Tite J.P., Jones B., Janeway C.A. Jr.;
RT   "Both a monoclonal antibody and antisera specific for determinants
RT   unique to individual cloned helper T cell lines can substitute for
RT   antigen and antigen-presenting cells in the activation of T cells.";
RL   J. Exp. Med. 158:836-856(1983).
//
RX   PubMed=31220119; DOI=10.1371/journal.pone.0218412;
RA   Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S.,
RA   Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H.,
RA   Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B.,
RA   Natoli M., Bauer B.A., Gollin S.M., Lewis D.W., Reid Y.A.;
RT   "Interlaboratory study to validate a STR profiling method for
RT   intraspecies identification of mouse cell lines.";
RL   PLoS ONE 14:E0218412-E0218412(2019).
//