Cellosaurus Caki-2 (CVCL_0235)
Cell line name | Caki-2 | ||||||||||||||||||||||||||||||||||||
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Synonyms | CAKI-2; CaKi-2; caki-2; CAKI 2; Caki 2; Caki2; CAKI2 | ||||||||||||||||||||||||||||||||||||
Accession | CVCL_0235 | ||||||||||||||||||||||||||||||||||||
Resource Identification Initiative | To cite this cell line use: Caki-2 (RRID:CVCL_0235) | ||||||||||||||||||||||||||||||||||||
Comments | Problematic cell line: Misclassified. Originally thought to be a clear cell renal cell carcinoma but shown to be from a papillary renal cell carcinoma (PubMed=17409424; PubMed=27993170). Part of: Cancer Dependency Map project (DepMap) (includes Cancer Cell Line Encyclopedia - CCLE). Part of: MD Anderson Cell Lines Project. From: Memorial Sloan Kettering Cancer Center; New York; USA. Registration: Memorial Sloan Kettering Cancer Center Office of Technology Development; SK2010-068. Doubling time: ~30-40 hours (DSMZ=ACC-54). Omics: Deep exome analysis. Omics: Deep quantitative proteome analysis. Omics: GPI-anchored proteins analysis by proteomics. Omics: Protein expression by reverse-phase protein arrays. Omics: SNP array analysis. Omics: Transcriptome analysis by microarray. Omics: Transcriptome analysis by RNAseq. Derived from sampling site: Kidney. | ||||||||||||||||||||||||||||||||||||
HLA typing | Source: PubMed=26589293
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Genome ancestry | Source: PubMed=30894373
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Disease | Papillary renal cell carcinoma (NCIt: C6975) Papillary renal cell carcinoma (ORDO: Orphanet_319298) | ||||||||||||||||||||||||||||||||||||
Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) | ||||||||||||||||||||||||||||||||||||
Sex of cell | Male | ||||||||||||||||||||||||||||||||||||
Age at sampling | 69Y | ||||||||||||||||||||||||||||||||||||
Category | Cancer cell line | ||||||||||||||||||||||||||||||||||||
STR profile | Source(s): ATCC; CCRID; CLS; COG; DSMZ; ECACC; KCLB; PubMed=25877200 Markers:
Run an STR similarity search on this cell line | ||||||||||||||||||||||||||||||||||||
Web pages | https://www.mskcc.org/research-advantage/support/technology/tangible-material/caki-2-human-renal-cell-line https://tcpaportal.org/mclp/ | ||||||||||||||||||||||||||||||||||||
Publications | DOI=10.1007/978-1-4757-1647-4_5 PubMed=327080; DOI=10.1093/jnci/59.1.221 PubMed=833871; DOI=10.1093/jnci/58.2.209 PubMed=571047 PubMed=6244232 PubMed=6935474; DOI=10.1093/jnci/66.2.239 PubMed=7459858 PubMed=6582512; DOI=10.1073/pnas.81.2.568 PubMed=3518877; DOI=10.3109/07357908609038260 PubMed=10723130; DOI=10.1038/sj.onc.1203449 PubMed=10929426; DOI=10.1007/s002400000103 PubMed=17409424; DOI=10.1158/0008-5472.CAN-06-4571 PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458 PubMed=22460905; DOI=10.1038/nature11003 PubMed=22949125; DOI=10.1002/ijc.27822 PubMed=25485619; DOI=10.1038/nbt.3080 PubMed=26589293; DOI=10.1186/s13073-015-0240-5 PubMed=26972028; DOI=10.1016/j.jprot.2016.03.008 PubMed=27141528; DOI=10.1016/j.dib.2016.04.001 PubMed=27993170; DOI=10.1186/s12943-016-0565-8 PubMed=28196595; DOI=10.1016/j.ccell.2017.01.005 PubMed=28489074; DOI=10.1038/ncomms15165 PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747 PubMed=31068700; DOI=10.1038/s41586-019-1186-3 PubMed=31978347; DOI=10.1016/j.cell.2019.12.023 | ||||||||||||||||||||||||||||||||||||
Cross-references | |||||||||||||||||||||||||||||||||||||
Cell line collections | ATCC; HTB-47
BCRJ; 0408 CLS; 300140 DSMZ; ACC-54 ECACC; 93120819 ICLC; HTL95029 IZSLER; BS TCL 8 KCLB; 30047 | ||||||||||||||||||||||||||||||||||||
Cell line databases/resources | CLO; CLO_0002177
MCCL; MCC:0000124 CLDB; cl625 CLDB; cl626 CLDB; cl627 CLDB; cl629 CCRID; 1101HUM-PUMC000337 Cell_Model_Passport; SIDM01546 DepMap; ACH-000234 DSMZCellDive; ACC-54 IGRhCellID; Caki2 | ||||||||||||||||||||||||||||||||||||
Anatomy/cell type resources | BTO; BTO:0006204 | ||||||||||||||||||||||||||||||||||||
Biological sample resources | 4DN; 4DNSRDD5W2FZ
BioSample; SAMN01821542 BioSample; SAMN01821619 BioSample; SAMN03471873 BioSample; SAMN10988361 ENCODE; ENCBS074UKQ ENCODE; ENCBS461KDA ENCODE; ENCBS611WID ENCODE; ENCBS768KGZ ENCODE; ENCBS787YGO | ||||||||||||||||||||||||||||||||||||
Chemistry resources | ChEMBL-Cells; CHEMBL3308071
ChEMBL-Targets; CHEMBL613852 PharmacoDB; Caki2_164_2019 PubChem_Cell_line; CVCL_0235 | ||||||||||||||||||||||||||||||||||||
Encyclopedic resources | Wikidata; Q54808377 | ||||||||||||||||||||||||||||||||||||
Experimental variables resources | EFO; EFO_0002150 | ||||||||||||||||||||||||||||||||||||
Gene expression databases | ArrayExpress; E-MTAB-38
ArrayExpress; E-MTAB-2706 ArrayExpress; E-MTAB-2770 GEO; GSM374478 GEO; GSM886903 GEO; GSM887968 | ||||||||||||||||||||||||||||||||||||
Polymorphism and mutation databases | Cosmic; 687941
Cosmic; 874612 Cosmic; 877458 Cosmic; 979706 Cosmic; 982278 Cosmic; 1152536 Cosmic; 2520633 IARC_TP53; 30022 LiGeA; CCLE_157 Progenetix; CVCL_0235 | ||||||||||||||||||||||||||||||||||||
Proteomic databases | PRIDE; PXD000335
PRIDE; PXD003105 | ||||||||||||||||||||||||||||||||||||
Sequence databases | EGA; EGAS00001000610 | ||||||||||||||||||||||||||||||||||||
Entry history | |||||||||||||||||||||||||||||||||||||
Entry creation | 04-Apr-2012 | ||||||||||||||||||||||||||||||||||||
Last entry update | 21-Mar-2023 | ||||||||||||||||||||||||||||||||||||
Version number | 34 |