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Cellosaurus C8166/45 (CVCL_0195)

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Cell line name C8166/45
Synonyms C81-66/45; C8166-45; C63/CRII-2
Accession CVCL_0195
Resource Identification Initiative To cite this cell line use: C8166/45 (RRID:CVCL_0195)
Comments Population: Caucasian.
Transformant: NCBI_TaxID; 11908; Human T-lymphotropic virus 1 (HTLV-1).
Derived from site: In situ; Umbilical cord blood; UBERON=UBERON_0012168.
Sequence variations
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Lys (c.181C>A); ClinVar=VCV000073058; Zygosity=Heterozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1099 (C8166)
Sex of cell Male
Age at sampling <1D
Category Transformed cell line
STR profile Source(s): PubMed=28357668; PubMed=32938764

Markers:
AmelogeninX,Y
CSF1PO10 (PubMed=32938764)
10,11 (PubMed=28357668)
D3S135815,16
D5S81812
D7S8209,10
D8S117911,14
D13S31710,11
D16S53912,13
D18S5114,17
D21S1127,30
FGA21,22
Penta D11,15
Penta E7,11
TH016,9.3
TPOX11
vWA15,16

Run an STR similarity search on this cell line
Publications

PubMed=6412453; DOI=10.1016/0042-6822(83)90395-1
Syed Zaki Salahuddin, Phillip D. Markham, Flossie Wong-Staal, Genoveffa Franchini, Vaniambadi S. Kalyanaraman, Robert Charles Gallo;
Restricted expression of human T-cell leukemia/lymphoma virus (HTLV) in transformed human umbilical cord blood lymphocytes.
Virology 129:51-64(1983)

PubMed=28357668; DOI=10.1007/978-1-4939-6872-5_11
Vittoria Raimondi, Sonia Anna Minuzzo, Vincenzo Ciminale, Donna M. D'Agostino;
STR profiling of HTLV-1-infected cell lines.
Methods Mol. Biol. 1582:143-154(2017)

PubMed=32938764; DOI=10.1128/JVI.01334-20; PMCID=PMC7654282
Melissa Victoria Fernandez, Huxley K. Hoffman, Nairi Pezeshkian, Philip R. Tedbury, Schuyler B. van Engelenburg, Eric O. Freed;
Elucidating the basis for permissivity of the MT-4 T-cell line to replication of an HIV-1 mutant lacking the gp41 cytoplasmic tail.
J. Virol. 94:e01334.20.1-e01334.20.27(2020)

Cross-references
Cell line collections (Providers) BEI_Resources; ARP-404
Cell line databases/resources MCCL; MCC:0000086
Encyclopedic resources Wikidata; Q54808258
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number19