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Cellosaurus B16-F1 (CVCL_0158)

[Text version]

Cell line name B16-F1
Synonyms B16/F1; B16 F1; B16F1
Accession CVCL_0158
Resource Identification Initiative To cite this cell line use: B16-F1 (RRID:CVCL_0158)
Comments Characteristics: Obtained from the pulmonary melanoma module of the 1st serial passage of the B16-F0 parent cell line in C57BL/6 mice.
Characteristics: Has a low metastatic potential.
Doubling time: 22 hours (PubMed=1109790).
Karyotypic information: Near tetraploid karyotype (PubMed=33596583).
Omics: Array-based CGH.
Omics: SNP array analysis.
Derived from sampling site: Skin.
Disease Mouse melanoma (NCIt: C21790)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Parent: CVCL_0604 (B16-F0)
Children:
CVCL_X605 (B16-Blue IFN-alpha/beta)CVCL_X604 (B16-Blue IFN-gamma)CVCL_X602 (B16-Blue ISG)
CVCL_A4CK (B16-F1-Luc2)CVCL_UJ41 (B16-F5)CVCL_ZF67 (B16-R1)
Sex of cell Male
Category Cancer cell line
STR profile Source(s): PubMed=31220119

Markers:
Mouse STR 1-117,18
Mouse STR 1-219,20
Mouse STR 2-116
Mouse STR 3-214,15
Mouse STR 4-220.3,21.3
Mouse STR 5-516,20
Mouse STR 6-418,19
Mouse STR 6-715
Mouse STR 7-126.2
Mouse STR 8-116,17
Mouse STR 11-216,17
Mouse STR 12-117,18
Mouse STR 13-117,18
Mouse STR 15-322.3,23.3
Mouse STR 17-215,16,17
Mouse STR 18-315,16
Mouse STR 19-213
Mouse STR X-128

Run an STR similarity search on this cell line
Publications

PubMed=1109790
Fidler I.J.
Biological behavior of malignant melanoma cells correlated to their survival in vivo.
Cancer Res. 35:218-224(1975)

PubMed=210294; DOI=10.1093/jnci/61.2.523
Niles R.M., Makarski J.S.
Control of melanogenesis in mouse melanoma cells of varying metastatic potential.
J. Natl. Cancer Inst. 61:523-526(1978)

PubMed=6498800; DOI=10.1016/0304-3835(84)90080-6
Wosko T.J., Ferrara D.T., Sartori L.S.
Histological comparison of the B16 melanoma and its F1 variant.
Cancer Lett. 24:57-63(1984)

PubMed=6539703; DOI=10.1016/0277-5379(84)90015-4
Weinreb A., Travo P.
Discrimination between human melanoma cell lines by fluorescence anisotropy.
Eur. J. Cancer Clin. Oncol. 20:673-677(1984)

PubMed=11833741; DOI=10.1016/S0024-3205(01)01454-0
Nakamura K., Yoshikawa N., Yamaguchi Y., Kagota S., Shinozuka K., Kunitomo M.
Characterization of mouse melanoma cell lines by their mortal malignancy using an experimental metastatic model.
Life Sci. 70:791-798(2002)

PubMed=22797548; DOI=10.3892/ijo.2012.1548
Liersch R., Shin J.W., Bayer M., Schwoppe C., Schliemann C., Berdel W.E., Mesters R., Detmar M.
Analysis of a novel highly metastatic melanoma cell line identifies osteopontin as a new lymphangiogenic factor.
Int. J. Oncol. 41:1455-1463(2012)

PubMed=25277546; DOI=10.1186/1471-2164-15-847
Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. III, Pardo-Manuel de Villena F.
SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.
BMC Genomics 15:847.1-847.11(2014)

PubMed=31220119; DOI=10.1371/journal.pone.0218412
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

PubMed=33596583; DOI=10.1159/000513174
Piaszinski K., Rincic M., Liehr T., Azawi S.
Molecular cytogenetic characterization of the murine melanoma cell lines S91 clone M3 and B16-F1 with variant B16-4A5.
Cytogenet. Genome Res. 161:82-92(2021)

Cross-references
Cell line collections ATCC; CRL-6323
BCRC; 60030
BCRJ; 0045
CCTCC; GDC0039
CLS; 400122
ECACC; 92101203
KCLB; 80007
NCI-DTP; B16F1
RCB; RCB2649
TKG; TKG 0347
Cell line databases/resources CLO; CLO_0001793
CLO; CLO_0050764
MCCL; MCC:0000050
CLDB; cl337
CLDB; cl338
CCRID; 1101MOU-PUMC000365
CCRID; 4201MOU-CCTCC00039
Lonza; 1278
TOKU-E; 581
Anatomy/cell type resources BTO; BTO:0003853
Biological sample resources BioSample; SAMN11397654
Chemistry resources ChEMBL-Cells; CHEMBL4295385
ChEMBL-Targets; CHEMBL4296402
PubChem_Cell_line; CVCL_0158
Encyclopedic resources Wikidata; Q54752433
Proteomic databases PRIDE; PXD018083
Entry history
Entry creation04-Apr-2012
Last entry update15-Dec-2022
Version number25