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Cellosaurus NTERA-2 (CVCL_0034)

[Text version]
Cell line name NTERA-2
Synonyms NTera-2; Ntera-2; NTera 2; NTERA2; NTera2; N-Tera-2; NT-2; NT2
Accession CVCL_0034
Resource Identification Initiative To cite this cell line use: NTERA-2 (RRID:CVCL_0034)
Comments Population: Caucasian.
Doubling time: ~50-60 hours (DSMZ=ACC-527).
Omics: Deep antibody staining analysis.
Omics: Deep quantitative proteome analysis.
Omics: SNP array analysis.
Omics: Transcriptome analysis by RNAseq.
Derived from site: Metastatic; Lung; UBERON=UBERON_0002048.
HLA typing Source: PubMed=16919167
Class I
HLA-AA*01
HLA-BB*08
HLA-CC*07
Class II
HLA-DQDQB1*02
HLA-DRDRB1*03
DRB3*01

Source: PubMed=26589293
Class I
HLA-AA*01:01,01:01
HLA-BB*08:01,37:04
HLA-CC*07:01,07:01
Class II
HLA-DRDRB1*03:01,14:76
Disease Embryonal carcinoma (NCIt: C3752)
Embryonal carcinoma (ORDO: Orphanet_180226)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_2777 (Tera-2)
Children:
CVCL_4U33 (NT2-B9)CVCL_3407 (NT2-D1)CVCL_4U27 (NT2-D3)
CVCL_K047 (NT2-Rho0)CVCL_C0QJ (NTERA-2-R)
Sex of cell Male
Age at sampling 22Y
Category Cancer cell line
STR profile Source(s): DSMZ; PubMed=16919167; PubMed=25877200

Markers:
AmelogeninX,Y
CSF1PO10,12
D2S133822,25
D3S135816
D5S8189,12
D7S82010,12
D8S117913,15
D13S31713
D16S53911,12,13
D18S5114
D19S43314
D21S1130,31
FGA23
Penta D12,13
Penta E5,14
TH019.3
TPOX8
vWA18,19

Run an STR similarity search on this cell line
Web pages https://en.wikipedia.org/wiki/NTERA-2
https://www.proteinatlas.org/learn/cellines
Publications

PubMed=6694356
Andrews P.W., Damjanov I., Simon D., Banting G.S., Carlin C.R., Dracopoli N.C., Fogh J.
Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro.
Lab. Invest. 50:147-162(1984)

PubMed=3293662; DOI=10.1016/0304-419X(88)90003-0
Andrews P.W.
Human teratocarcinomas.
Biochim. Biophys. Acta 948:17-36(1988)

PubMed=16919167; DOI=10.1186/1741-7007-4-28
Josephson R., Sykes G.R., Liu Y., Ording C.J., Xu W.-N., Zeng X.-M., Shin S., Loring J.F., Maitra A., Rao M.S., Auerbach J.M.
A molecular scheme for improved characterization of human embryonic stem cell lines.
BMC Biol. 4:28.1-28.13(2006)

PubMed=25485619; DOI=10.1038/nbt.3080
Klijn C., Durinck S., Stawiski E.W., Haverty P.M., Jiang Z.-S., Liu H.-B., Degenhardt J., Mayba O., Gnad F., Liu J.-F., Pau G., Reeder J., Cao Y., Mukhyala K., Selvaraj S.K., Yu M.-M., Zynda G.J., Brauer M.J., Wu T.D., Gentleman R.C., Manning G., Yauch R.L., Bourgon R., Stokoe D., Modrusan Z., Neve R.M., de Sauvage F.J., Settleman J., Seshagiri S., Zhang Z.-M.
A comprehensive transcriptional portrait of human cancer cell lines.
Nat. Biotechnol. 33:306-312(2015)

PubMed=25877200; DOI=10.1038/nature14397
Yu M., Selvaraj S.K., Liang-Chu M.M.Y., Aghajani S., Busse M., Yuan J., Lee G., Peale F.V., Klijn C., Bourgon R., Kaminker J.S., Neve R.M.
A resource for cell line authentication, annotation and quality control.
Nature 520:307-311(2015)

PubMed=26589293; DOI=10.1186/s13073-015-0240-5
Scholtalbers J., Boegel S., Bukur T., Byl M., Goerges S., Sorn P., Loewer M., Sahin U., Castle J.C.
TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression.
Genome Med. 7:118.1-118.7(2015)

PubMed=35084545; DOI=10.1007/s00345-022-03936-1
Fichtner A., Bohnenberger H., Elakad O., Richter A., Lenz C., Oing C., Strobel P., Kueffer S., Nettersheim D., Bremmer F.
Proteomic profiling of cisplatin-resistant and cisplatin-sensitive germ cell tumour cell lines using quantitative mass spectrometry.
World J. Urol. 40:373-383(2022)

Cross-references
Cell line collections (Providers) DSMZ; ACC-527
IBRC; C10509
RSCB; RSCB0150
Cell line databases/resources CLO; CLO_0008208
CCRID; 1101HUM-PUMC000019
DSMZCellDive; ACC-527
Anatomy/cell type resources BTO; BTO:0000891
Biological sample resources BioSample; SAMN03472969
Chemistry resources ChEMBL-Cells; CHEMBL3308505
ChEMBL-Targets; CHEMBL614205
PharmacoDB; NTERA2_1167_2019
PubChem_Cell_line; CVCL_0034
Encyclopedic resources Wikidata; Q17092091
Experimental variables resources EFO; EFO_0002959
Gene expression databases ArrayExpress; E-MTAB-2706
Polymorphism and mutation databases Cosmic; 821809
Cosmic; 2439936
Cosmic; 2560242
Cosmic; 2806394
Cosmic; 2807075
Proteomic databases PRIDE; PXD030251
Sequence databases EGA; EGAS00001000610
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number29