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Loveless; Morphological, biological, biochemical, and karyotypic characteristics of human pancreatic ductal adenocarcinoma Capan-2 in tissue culture and the nude mouse. Cancer Res. 46:5810-5815(1986) PubMed=3518877; DOI=10.3109/07357908609038260 Jorgen Fogh; Human tumor lines for cancer research. Cancer Invest. 4:157-184(1986) PubMed=1764370; DOI=10.1038/bjc.1991.467; PMCID=PMC1977874 Claire M. Barton, Susan Louise Staddon, Christine M. Hughes, Peter A. Hall, Catriona O'Sullivan, Gunter Kloppel, Belinda Theis, Ronald Christopher Gordon Russell, John Neoptolemos, Robin Charles Noel Williamson, David Philip Lane, Nicholas Robert Lemoine; Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer. Br. J. Cancer 64:1076-1082(1991) PubMed=1630814 Bruce Anthony Ruggeri, Shi-Yu Zhang, Jorge Caamano, Marion DiRado, Stuart Dale Flynn, Andres J.P. Klein-Szanto; Human pancreatic carcinomas and cell lines reveal frequent and multiple alterations in the p53 and Rb-1 tumor-suppressor genes. Oncogene 7:1503-1511(1992) PubMed=8426738 Holger Kalthoff, Wolff Helmut Schmiegel, Christian Roeder, Daniela Kasche, Andreas Schmidt, Georg Lauer, Heinz-Gunter Thiele, Georg Honold, Klaus Pantel, Gert Riethmuller, Ewalt Scherer ...Show all 14 authors... , Julian Maurer, Heiko Maacke, Wolfgang Deppert; Show fewer authors p53 and K-RAS alterations in pancreatic epithelial cell lesions. Oncogene 8:289-298(1993) PubMed=7809022; DOI=10.1097/00006676-199409000-00018 Shoichiro Sumi, R. Daniel Beauchamp, Courtney M. Townsend Jr., Parviz M. Pour, Jin Ishizuka, James C. Thompson; Lovastatin inhibits pancreatic cancer growth regardless of RAS mutation. Pancreas 9:657-661(1994) PubMed=7961102; DOI=10.1111/j.1349-7006.1994.tb02898.x; PMCID=PMC5919355 Hirofumi Suwa, Tsunehiro Yoshimura, Nozomi Yamaguchi, Kazunori Kanehira, Tadao Manabe, Masayuki Imamura, Hiroshi Hiai, Manabu Fukumoto; K-ras and p53 alterations in genomic DNA and transcripts of human pancreatic adenocarcinoma cell lines. Jpn. J. Cancer Res. 85:1005-1014(1994) PubMed=7972006; DOI=10.1073/pnas.91.23.11045; PMCID=PMC45163 Aikou Okamoto, Douglas J. Demetrick, Elisa A. Spillare, Koichi Hagiwara, S. Perwez Hussain, William P. Bennett, Kathleen Forrester, Brenda Isen Gerwin, Manuel Serrano, David H. Beach, Curtis Craig Harris; Mutations and altered expression of p16INK4 in human cancer. Proc. Natl. Acad. Sci. U.S.A. 91:11045-11049(1994) PubMed=8026879; DOI=10.1002/ijc.2910580207 Georgina Berrozpe, James Schaeffer, Miguel Angel Peinado, Francisco X. Real, Manuel Perucho; Comparative analysis of mutations in the p53 and K-ras genes in pancreatic cancer. Int. J. Cancer 58:185-191(1994) PubMed=8194712; DOI=10.1016/0016-5085(94)90422-7 Babette Simon, Rolf Weinel, Martin Hohne, Jutta Watz, Jorg Schmidt, Gunther Kortner, Rudolf Arnold; Frequent alterations of the tumor suppressor genes p53 and DCC in human pancreatic carcinoma. Gastroenterology 106:1645-1651(1994) PubMed=8286197; DOI=10.1038/bjc.1994.24; PMCID=PMC1968784 Johannes-Matthias Lohr, Birgit Trautmann, Martin Gottler, Shirley Peters, Ira Zauner, Bernard Maillet, Gunter Kloppel; Human ductal adenocarcinomas of the pancreas express extracellular matrix proteins. Br. J. Cancer 69:144-151(1994) PubMed=10027410; DOI=10.1016/S0002-9440(10)65298-4; PMCID=PMC1850008 B. Michael Ghadimi, Evelin Schrock, Robert L. Walker, Danny Wangsa, Annukka Jauho, Paul S. Meltzer, Thomas Ried; Specific chromosomal aberrations and amplification of the AIB1 nuclear receptor coactivator gene in pancreatic carcinomas. Am. J. Pathol. 154:525-536(1999) PubMed=11169957; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1014>3.0.CO;2-U Christine Wallrapp, Susanne Hahnel, Wolfgang Boeck, Anja Soder, Antoaneta Mincheva, Peter Lichter, Gerhard Leder, Frank Gansauge, Claudio Sorio, Aldo Scarpa, Thomas M. Gress; Loss of the Y chromosome is a frequent chromosomal imbalance in pancreatic cancer and allows differentiation to chronic pancreatitis. Int. J. Cancer 91:340-344(2001) PubMed=11169959; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1049>3.0.CO;2-C Vorapan Sirivatanauksorn, Yongyut Sirivatanauksorn, Patricia A. Gorman, Jeffrey M. Davidson, Denise Sheer, Patrick S. Moore, Aldo Scarpa, Paul A.W. Edwards, Nicholas Robert Lemoine; Non-random chromosomal rearrangements in pancreatic cancer cell lines identified by spectral karyotyping. Int. J. Cancer 91:350-358(2001) PubMed=11668190; DOI=10.1177/002215540104901105 Hilmar Quentmeier, Mary Osborn, Julia Reinhardt, Margarete Zaborski, Hans Gunther Drexler; Immunocytochemical analysis of cell lines derived from solid tumors. J. Histochem. Cytochem. 49:1369-1378(2001) PubMed=12692724; DOI=10.1007/s00428-003-0784-4 Bence Sipos, Simone Moser, Holger Kalthoff, Virag Torok, Johannes-Matthias Lohr, Gunter Kloppel; A comprehensive characterization of pancreatic ductal carcinoma cell lines: towards the establishment of an in vitro research platform. Virchows Arch. 442:444-452(2003) PubMed=12800145; DOI=10.1002/gcc.10218 Jose Adelaide, Huai-En Huang, Anne Murati, Amber E. Alsop, Beatrice Orsetti, Marie-Joelle Mozziconacci, Cornel Popovici, Christophe Ginestier, Anne Letessier, Celine Basset, Celine Courtay-Cahen ...Show all 16 authors... , Jocelyne Jacquemier, Charles Theillet, Daniel Birnbaum, Paul A.W. Edwards, Max Chaffanet; Show fewer authors A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene. Genes Chromosomes Cancer 37:333-345(2003) PubMed=14695172 Christine A. Iacobuzio-Donahue, Raheela Ashfaq, Anirban Maitra, Nazmi Volkan Adsay, Grace L.-C. Shen-Ong, Karin Berg, Michael Anthony Hollingsworth, John Lemuel Cameron, Charles J. Yeo, Scott E. Kern, Michael Gilbert Goggins, Ralph H. Hruban; Highly expressed genes in pancreatic ductal adenocarcinomas: a comprehensive characterization and comparison of the transcription profiles obtained from three major technologies. Cancer Res. 63:8614-8622(2003) PubMed=15126341; DOI=10.1158/0008-5472.CAN-03-3159 Markus Heidenblad, Eric F.P.M. Schoenmakers, Tord Jonson, Ludmila Gorunova, Joris A. Veltman, Ad Geurts van Kessel, Mattias Hoglund; Genome-wide array-based comparative genomic hybridization reveals multiple amplification targets and novel homozygous deletions in pancreatic carcinoma cell lines. Cancer Res. 64:3052-3059(2004) PubMed=15367885; DOI=10.1097/00006676-200410000-00004 Panayiotis Loukopoulos, Kengo Kanetaka, Masaaki Takamura, Tatsuhiro Shibata, Michiie Sakamoto, Setsuo Hirohashi; Orthotopic transplantation models of pancreatic adenocarcinoma derived from cell lines and primary tumors and displaying varying metastatic activity. Pancreas 29:193-203(2004) PubMed=15688027; DOI=10.1038/sj.onc.1208383 Markus Heidenblad, David Lindgren, Joris A. Veltman, Tord Jonson, Eija H. Mahlamaki, Ludmila Gorunova, Ad Geurts van Kessel, Eric F.P.M. Schoenmakers, Mattias Hoglund; Microarray analyses reveal strong influence of DNA copy number alterations on the transcriptional patterns in pancreatic cancer: implications for the interpretation of genomic amplifications. Oncogene 24:1794-1801(2005) PubMed=15770730; DOI=10.3748/wjg.v11.i10.1521; PMCID=PMC4305696 Jian-Hua Ma, Emilia Patrut, Jan Schmidt, Hanns-Peter Knaebel, Markus Wolfgang Buchler, Alexandra Marten; Synergistic effects of interferon-alpha in combination with chemoradiation on human pancreatic adenocarcinoma. World J. Gastroenterol. 11:1521-1528(2005) PubMed=16957166; DOI=10.1369/jhc.6A7001.2006; PMCID=PMC3958123 Ann-Catrin Andersson, Sara Stromberg, Helena Backvall, Caroline Kampf, Mathias Uhlen, Kenneth Wester, Fredrik Ponten; Analysis of protein expression in cell microarrays: a tool for antibody-based proteomics. J. Histochem. 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Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers. Cancer Res. 70:2158-2164(2010) PubMed=20418756; DOI=10.1097/MPA.0b013e3181c15963; PMCID=PMC2860631 Emily L. Deer, Jessica Gonzalez-Hernandez, Jill D. Coursen, Jill E. Shea, Josephat Gichuhi Ngatia, Courtney Lynne Scaife, Matthew A. Firpo, Sean Jordan Mulvihill; Phenotype and genotype of pancreatic cancer cell lines. Pancreas 39:425-435(2010) PubMed=22460905; DOI=10.1038/nature11003; PMCID=PMC3320027 Jordi Ginesta Barretina, Giordano Caponigro, Nicolas Stransky, Kavitha Venkatesan, Adam A. Margolin, Sungjoon Kim, Christopher J. Wilson, Joseph Lehar, Gregory V. Kryukov, Dmitriy Sonkin, Anupama Reddy ...Show all 61 authors... , Manway Liu, Lauren Murray, Michael F. Berger, John E. Monahan, Paula Morais, Jodi Meltzer, Adam Korejwa, Judit Jane-Valbuena, Felipa A. Mapa, Joseph Thibault, Eva Bric-Furlong, Pichai Raman, Aaron Shipway, Ingo H. Engels, Jill Cheng, Guo-Ying K. Yu, Jian-Jun Yu, Peter Aspesi Jr., Melanie de Silva, Kalpana Jagtap, Michael D. Jones, Li Wang, Charles Hatton, Emanuele Palescandolo, Supriya Gupta, Scott Mahan, Carrie Sougnez, Robert C. Onofrio, Ted Liefeld, Laura E. MacConaill, Wendy Winckler, Michael Reich, Nan-Xin Li, Jill P. Mesirov, Stacey B. Gabriel, Gad Getz, Kristin Ardlie, Vivien Chan, Vic E. Myer, Barbara L. Weber, Jeff Porter, Markus Warmuth, Peter Finan, Jennifer L. Harris, Matthew Langer Meyerson, Todd Robert Golub, Michael P. Morrissey, William Raj Sellers, Robert Schlegel, Levi Alexander Garraway; Show fewer authors The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature 483:603-607(2012) PubMed=22585861; DOI=10.1158/2159-8290.CD-11-0224; PMCID=PMC5057396 Richard Marcotte, Kevin R. Brown, Fernando Jose Suarez Saiz, Azin Sayad, Konstantina Karamboulas, Paul M. Krzyzanowski, Fabrice Sircoulomb, Mauricio Medrano, Yaroslav Fedyshyn, Judice Lie-Yong Koh, Dewald van Dyk ...Show all 28 authors... , Bohdana Fedyshyn, Marianna Luhova, Glauber C. Brito, Franco J. Vizeacoumar, Frederick S. Vizeacoumar, Alessandro Datti, Dahlia Kasimer, Alla Buzina, Patricia Mero, Christine Misquitta, Josee Normand, Maliha Haider, Troy Ketela, Jeffrey L. Wrana, Robert Rottapel, Benjamin G. Neel, Jason Moffat; Show fewer authors Essential gene profiles in breast, pancreatic, and ovarian cancer cells. Cancer Discov. 2:172-189(2012) PubMed=24700732; DOI=10.1002/humu.22556; PMCID=PMC4451114 Bernard Leroy, Luc Girard, Antoinette Hollestelle, John D. Minna, Adi F. Gazdar, Thierry Soussi; Analysis of TP53 mutation status in human cancer cell lines: a reassessment. Hum. Mutat. 35:756-765(2014) PubMed=25167228; DOI=10.1038/bjc.2014.475; PMCID=PMC4453732 Habib Hamidi, Ming Lu, Kevin Chau, Lee Anderson, Marlena Schoenberg Fejzo, Charles Ginther, Ronald Linnartz, Angela Zubel, Dennis Joseph Slamon, Richard Samuel Finn; KRAS mutational subtype and copy number predict in vitro response of human pancreatic cancer cell lines to MEK inhibition. Br. J. Cancer 111:1788-1801(2014) PubMed=25485619; DOI=10.1038/nbt.3080 Christiaan Klijn, Steffen Durinck, Eric W. Stawiski, Peter M. Haverty, Zhao-Shi Jiang, Han-Bin Liu, Jeremiah Degenhardt, Oleg Mayba, Florian Gnad, Jin-Feng Liu, Gregoire Pau ...Show all 30 authors... , Jens Reeder, Yi Cao, Kiran Mukhyala, Suresh K. Selvaraj, Ma-Mie Yu, Gregory J. Zynda, Matthew J. Brauer, Thomas D. Wu, Robert Clifford Gentleman, Gerard Manning, Robert L. Yauch, Richard Bourgon, David Stokoe, Zora Modrusan, Richard M. Neve, Frederic J. de Sauvage, Jeffrey Settleman, Somasekar Seshagiri, Ze-Min Zhang; Show fewer authors A comprehensive transcriptional portrait of human cancer cell lines. Nat. Biotechnol. 33:306-312(2015) PubMed=25877200; DOI=10.1038/nature14397 Ma-Mie Yu, Suresh K. Selvaraj, May M.Y. Liang-Chu, Sahar Aghajani, Matthew Busse, Jean Yuan, Genee Lee, Franklin V. Peale, Christiaan Klijn, Richard Bourgon, Joshua S. Kaminker, Richard M. Neve; A resource for cell line authentication, annotation and quality control. Nature 520:307-311(2015) PubMed=26216984; DOI=10.1073/pnas.1501605112; PMCID=PMC4538616 Anneleen Daemen, David Peterson, Nisebita Sahu, Ron McCord, Xiang-Nan Du, Bonnie Liu, Katarzyna Kowanetz, Rebecca Hong, John Moffat, Min Gao, Aaron Boudreau ...Show all 22 authors... , Rana Mroue, Laura Corson, Thomas O'Brien, Jing Qing, Deepak Sampath, Mark Merchant, Robert L. Yauch, Gerard Manning, Jeffrey Settleman, Georgia Hatzivassiliou, Marie Evangelista; Show fewer authors Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors. Proc. Natl. Acad. Sci. U.S.A. 112:E4410-E4417(2015) PubMed=26589293; DOI=10.1186/s13073-015-0240-5; PMCID=PMC4653878 Jelle Scholtalbers, Sebastian Boegel, Thomas Bukur, Marius Byl, Sebastian Goerges, Patrick Sorn, Martin Loewer, Ugur Sahin, John C. Castle; TCLP: an online cancer cell line catalogue integrating HLA type, predicted neo-epitopes, virus and gene expression. Genome Med. 7:118.1-118.7(2015) PubMed=27259358; DOI=10.1074/mcp.M116.058313; PMCID=PMC4974343 Emily S. Humphrey, Shih-Ping Su, Adnan M. Nagrial, Falko Hochgrafe, Marina Pajic, Gillian M. Lehrbach, Robert G. Parton, Alpha S. Yap, Lisa G. Horvath, David K. Chang, Andrew Victor Biankin ...Show all 13 authors... , Jian-Min Wu, Roger J. Daly; Show fewer authors Resolution of novel pancreatic ductal adenocarcinoma subtypes by global phosphotyrosine profiling. Mol. Cell. Proteomics 15:2671-2685(2016) PubMed=27397505; DOI=10.1016/j.cell.2016.06.017; PMCID=PMC4967469 Francesco Iorio, Theo A. Knijnenburg, Daniel J. Vis, Graham Robert Bignell, Michael Patrick Menden, Michael Schubert, Nanne Aben, Emanuel Goncalves, Syd Barthorpe, Howard Lightfoot, Thomas Cokelaer ...Show all 39 authors... , Patricia Greninger, Ewald van Dyk, Han Chang, Heshani de Silva, Holger Heyn, Xian-Ming Deng, Regina K. Egan, Qing-Song Liu, Tatiana Mironenko, Xeni Mitropoulos, Laura Richardson, Jin-Hua Wang, Ting-Hu Zhang, Sebastian Moran, Sergi Sayols, Maryam Soleimani, David Tamborero, Nuria Lopez-Bigas, Petra Ross-Macdonald, Manel Esteller, Nathanael S. Gray, Daniel Arie Haber, Michael Rudolf Stratton, Cyril Henri Benes, Lodewyk F.A. Wessels, Julio Saez-Rodriguez, Ultan McDermott, Mathew J. Garnett; Show fewer authors A landscape of pharmacogenomic interactions in cancer. Cell 166:740-754(2016) PubMed=30894373; DOI=10.1158/0008-5472.CAN-18-2747; PMCID=PMC6445675 Julie Dutil, Zhi-Hua Chen, Alvaro N.A. Monteiro, Jamie K. Teer, Steven A. Eschrich; An interactive resource to probe genetic diversity and estimated ancestry in cancer cell lines. Cancer Res. 79:1263-1273(2019) PubMed=31037374; DOI=10.1007/s00216-019-01814-1 Simon Lagies, Manuel Schlimpert, Lukas M. Braun, Michel Kather, Johannes Plagge, Thalia Erbes, Uwe A. Wittel, Bernd Kammerer; Unraveling altered RNA metabolism in pancreatic cancer cells by liquid-chromatography coupling to ion mobility mass spectrometry. Anal. Bioanal. Chem. 411:6319-6328(2019) PubMed=31068700; DOI=10.1038/s41586-019-1186-3; PMCID=PMC6697103 Mahmoud Ghandi, Franklin W. Huang, Judit Jane-Valbuena, Gregory V. Kryukov, Christopher C. Lo, E. Robert McDonald 3rd, Jordi Ginesta Barretina, Ellen T. Gelfand, Craig M. Bielski, Hao-Xin Li, Kevin Hu ...Show all 68 authors... , Alexander Y. Andreev-Drakhlin, Jaegil Kim, Julian M. Hess, Brian J. Haas, Francois Aguet, Barbara A. Weir, Michael V. Rothberg, Brenton R. Paolella, Michael Scott Lawrence, Rehan Akbani, Yi-Ling Lu, Hong L. Tiv, Prafulla C. Gokhale, Antoine de Weck, Ali Amin Mansour, Coyin Oh, Juliann Shih, Kevin Hadi, Yanay Rosen, Jonathan Bistline, Kavitha Venkatesan, Anupama Reddy, Dmitriy Sonkin, Manway Liu, Joseph Lehar, Joshua M. Korn, Dale A. Porter, Michael D. Jones, Javad Golji, Giordano Caponigro, Jordan E. Taylor, Caitlin M. Dunning, Amanda L. Creech, Allison C. Warren, James M. McFarland, Mahdi Zamanighomi, Audrey Kauffmann, Nicolas Stransky, Marcin Imielinski, Yosef E. Maruvka, Andrew D. Cherniack, Aviad Tsherniak, Francisca Vazquez, Jacob D. Jaffe, Andrew Alan Lane, David M. Weinstock, Cory M. Johannessen, Michael P. Morrissey, Frank Stegmeier, Robert Schlegel, William Chun Hahn, Gad Getz, Gordon B. Mills, Jesse S. Boehm, Todd Robert Golub, Levi Alexander Garraway, William Raj Sellers; Show fewer authors Next-generation characterization of the Cancer Cell Line Encyclopedia. Nature 569:503-508(2019) PubMed=35839778; DOI=10.1016/j.ccell.2022.06.010; PMCID=PMC9387775 Emanuel Goncalves, Rebecca C. Poulos, Zhao-Xiang Cai, Syd Barthorpe, Srikanth S. Manda, Natasha Lucas, Alexandra Beck, Daniel Bucio-Noble, Michael Dausmann, Caitlin Hall, Michael Hecker ...Show all 32 authors... , Jennifer Koh, Howard Lightfoot, Sadia Mahboob, Iman Mali, James Morris, Laura Richardson, Akila J. Seneviratne, Rebecca Shepherd, Erin Sykes, Frances Thomas, Sara Valentini, Steven G. Williams, Yang-Xiu Wu, Dylan Xavier, Karen L. MacKenzie, Peter G. Hains, Brett Tully, Phillip James Robinson, Qing Zhong, Mathew J. Garnett, Roger Robert Reddel; Show fewer authors Pan-cancer proteomic map of 949 human cell lines. Cancer Cell 40:835-849.e8(2022) |