| Publication number |
CLPUB00657 |
|---|
| Authors |
Soji Fukumoto, Takahiko Tanigawa, Seiichi Yazaki, Yoshinori Tanaka; |
|---|
| Title |
Cytotoxicity of mouse macrophage cell line, A640-BB-2, against newborn larvae of Trichinella spiralis. |
|---|
| Citation |
Yonago Acta Med. 34:105-112(1991) |
|---|
| Web pages |
https://jglobal.jst.go.jp/en/detail?JGLOBAL_ID=200902081334195378 |
|---|
| Abstract |
The mouse macrophage cell line A640-BB-2 was cytotoxic against newborn
larvae (NBL) of Trichinella spiralis after activation by
lipopolysaccharide (LPS). Activated macrophages developed ridge-like
processes and spread more extensively on culture substrates than untreated
control cells. NBL that were cultured with activated, LPS-stimulated
macrophages for 72 h became inactive or were killed. These results
indicate that activated macrophages may play an important role in defence
against infection with Trichinella spiralis.
|
|---|
| Cell lines |
CVCL_JJ75; A640-BB-2 |
|---|
