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Cellosaurus publication CLPUB00502

Publication number CLPUB00502
Authors Li-Ming Shi, Wei-Shun He, Yu-Ze Chen;
Title Studies of mutagenicity of chemicals on red muntjac cells.
Citation Dong Wu Xue Yan Jiu 1:297-302(1980)
Web pages https://www.zoores.ac.cn/en/article/id/916
Abstract A diploid cell strain (KIZ-7901) of red muntjac (Muntiacus muntjak) has been established in our laboratory. The diploid chromosome number of red muntjac (male=7, female=6) is the lowest among all vertebrates, so it is a good assay system for the testing of chemical mutagens. We use N,N- methylene-bis(2-amino-1,3,4-thiadiazole) as the chemical mutagen. The experimental results show that the greater the dosage of this chemical uses and the longer the duration of the treatment lasts, the greater the rates of the sister chromatid exchanges (SCEs) are, especially the frequencies of chromosome aberrations.
Cell lines CVCL_WL31; KIZ-7901