| Abstract |
Cell lines are a valuable biological tool for carrying out researches in
physiology, virology, pharmacology, toxicology, cancer/carcinogenesis and
transgenic fields. Several "fish cell lines" have been developed from a
broad range of tissues by explant techniques, e.g., ovary, fin, swim
bladder, heart, spleen, liver, eye muscle, vertebrae, brain, skin. At
present, 50 fish cell lines from 24 different fish species are maintained
and cryopreserved in the National Repository of fish cell line (NRFC),
NBFGR. In the current review, the authors have discussed the national
status and advances in the development cell lines from different fish
species. Besides these, the importance of cell line characterization,
applications and cross-contamination have also been discussed briefly in
this review. The author feels that this review article will undoubtedly
serve an updated database for the scientists/researchers in the field of
pathology, toxicology, fishery science, and other life science disciplines
wherever needed for research.
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