| Publication number |
CLPUB00417 |
|---|
| Authors |
Takaaki Ishihara, George Eugene Moore, Avery Aba Sandberg; |
|---|
| Title |
The in vitro chromosome constitution of cells from human tumors. |
|---|
| Citation |
Cancer Res. 22:375-379(1962) |
|---|
| Web pages |
https://aacrjournals.org/cancerres/article/22/3/375/474943/ |
|---|
| Abstract |
The chromosome constitution was determined in nine established, long-term
cultures of cells obtained from the effusions or excised tissues of
cancer patients. The cultures were characterized by chromosome modes near
the triploid range (66-75), with a considerable spread of the chromosome
number about the mode. Analysis of the karyotypes revealed that most of
the chromosomes could be grouped superficially into the various groups
described for the normal human karyotype. The heteroploidy of the cells
was due to extrasomy of all groups, with the exception of group G, which
was usually in the diploid range. New, marker chromosomes were present in
most of the cell lines examined.
|
|---|
| Cell lines |
CVCL_RP63; RPMI-1922 |
|---|
