| Publication number |
CLPUB00380 |
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| Authors |
Hanada S., Tsubai F., Namba Y. |
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| Title |
The characteristics of T-cell lines derived from peripheral blood of patients with adult T-cell leukemia-lymphoma. |
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| Citation |
Recent Adv. RES Res. 25:124-133(1985) |
|---|
| Abstract |
Since Miyoshi et al. reported the first establishment of T-cell line
derived from a patient with adult T-cell leukemia (ATL), many T-cell
lines derived from patients with ATL were reported. These cell lines,
especially MT-1 were played important role in the etiological study of
ATL, such as detection of ATL associated antigen (ATLA) and finding
Of ATL virus (ATLV). Recent studies showed that ATLV and Human T-cell
leukemia virus type I (HTLV-I) isolated from T-cell lymphoma-leukemia
patients in USA are the same species and thought to cause ATL. However
the relation between ATLV/HTLV-I infection and leukemogenesis of ATL has
been unclear. Recently, we also established T-cell lines derived from
patients with adult T-cell leukemia-lymphoma (ATLL) and produced
monoclonal antibodies to one of these cell lines. In this paper, we report
the characteristics of these cell lines and the specificity of our
monoclonal antibodies.
|
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| Cell lines |
CVCL_G036; KUT-1 CVCL_G037; KUT-2 CVCL_G038; KUT-3 |
|---|
