| Publication number |
CLPUB00378 |
|---|
| Authors |
Bo Liu, Zhan-Min Wang, Xiao-Peng Wu, Chun-Sheng Liu, Zhao-Ting Li, Jun Liu; |
|---|
| Title |
Study of human gallbladder carcinoma cell line on its construction and biological behavior. |
|---|
| Citation |
Wai Ke Li Lun Yu Shi Jian 6:146-148(2001) |
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| Web pages |
https://oversea.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFD&dbname=CJFD2001&filename=WKLL200103010&uniplatform=OVERSEA |
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| Abstract |
Objective: To construct a human gallbladder carcinoma cell line and to
investigate its biological behavior.
Methods: GBC-SD, a human gallbladder carcinoma cell line was constructed
via the tissue culture. The biological behavior such as cell morphology,
cytokinetics, CEA and CA-199 secretion and growth pattern in
heteroimplantation were studied in vitro and in vivo respectively.
Results: The GBC-SD cells were mainly composed of square, polygonal and
spindal cells, the doubling time was 21.4h. The cell line could secret CEA
and CA-199 continuously. The histological features of implanted tumor in
nude mice were similar to those of the original one.
Conclusions: Being a new constructed gallbladder carcinoma cell line, the
GBC-SD cell line could be served as an experimental model for further
study.
|
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| Cell lines |
CVCL_6903; GBC-SD |
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