Cellosaurus publication CLPUB00375

Publication number	CLPUB00375
Authors	Takayuki Kamamoto, Hiroto Sakoda, Yoshio Taniguchi, Hiroshi Kamesaki, Kenkichi Kita, Hitoshi Ohno, Shirou Fukuhara, Yutaka Umadome, Tadashi Ohkubo, Yataro Yoshida, Haruto Uchino;
Title	Establishment and characterization of an Epstein-Barr virus-negative B cell lymphoma cell line with a 14q+ chromosome abnormality.
Citation	Naika Hokan 32:241-251(1985)
Web pages	https://eurekamag.com/research/005/384/005384527.php
Abstract	A cell line (KPB-L2) was established from the peripheral blood of a patient with diffuse Burkitt type lymphoma in a leukemic state. KPB-L2 expressed immunoglobulin M-kappa. on the surface as did the primary tumors and the original leukemic cells. KPB-L2 also expressed Ia-like antigen but lacked Epstein-Barr virus nuclear antigen. It exhibited a 14q+ marker chromosome, which was a result of a translocation between the long arms of chromosomes 8 and 14 [t(8;14)(q24;q32)], and the same 14q+ translocation was also found in the parental cells. This cell line may be useful for studying the significance of 14q+ rearrangement in the development of lymphoid malignancy.
Cell lines	CVCL_W861; KPB-L2