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Cellosaurus publication CLPUB00353

Publication number CLPUB00353
Authors Kung-Chong Chao, Heung-Tat Ng, Ming-Shyen Yen, Chi-Ching Chang;
Title Immunohistostain and in vitro tumor marker studies of cervical cancer cells (CC-135-VGH).
Citation J. Obstet. Gynecol. Rep. China 32:15-23(1993)
Web pages http://readopac3.ncl.edu.tw/nclserialFront/search/detail.jsp?sysId=0005388523&dtdId=000040&search_type=detail&la=ch
Abstract A human cervical carcinoma cell line, CC-135-VGH, has been established from a epidermoid carcinoma of the uterine cervix. The chromosome number of CC-135-VGH ranged from 44 to 48 with a modal number of 45. The cell doubling time was about 44 hours. Immunohistostain of CC-135-VGH cells for epithelial membrane antibody (EMA), desmin, vimentin and tumor markers CA-125, carcino-embryonic antigen (CEA) and human placenta alkaline phophatase (HPAP) were negative; only those of cytoskeleton, myoglobin and fibronectin were positive. The secretion of tumor markers by CC-135-VGH cells was also examined. The secretion of CA-125 was lower than 40mu/ml, followed by CEA (2 ng/ml) and HPAP (11 mIU/ml).
Cell lines CVCL_GT23; CC-135-VGH