| Abstract |
A human ovarian carcinoma cell line, OC-89-VGH, established from a
mucinous cystadenocarcinoma of the ovary. OC-89-VGH has a varied number of
chromosome number ranging from 69 to 80 with a model number of 75. The
doubling time of cells was 51 hours. Immunohistochemical studies of OC-89-VGH
cells for epithelial membrane antigen (EMA), desmin and fibronectin
were negative, while the markers of cytokeratin, myoglobin, vimentin, CA-125,
carcino-embryonic antigen (CEA) and human placental alkaline
phosphatase (PLAP) were all positive. The secretion of ectopic proteins by
OC-89-VGH cells was also investigated and it was highest in CA-125 (>600 U/ml),
followed by CEA (220 ng/ml) and PLAP (6 mIU/ml) secretion.
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