| Publication number |
CLPUB00300 |
|---|
| Authors |
Susanne Lange, Oskar-Ruger Kaaden; |
|---|
| Title |
Establishment of a cell line and detection of a retrovirus from bovine skin leukosis. |
|---|
| Citation |
(In book chapter) Fifth international symposium on bovine leukosis; Straub, Otto Christian (eds.); pp.529-534; Martinus Nijhoff Publishers; The Hague; Netherlands (1982) |
|---|
| Abstract |
We were able to establish a cell line from a skin tumour of a case of
bovine skin leukosis and to detect a formerly unknown bovine retrovirus,
that showed no antigenic and genetic relationship with BLV. Although the
SBL-H-12578 particles appear to be associated with some cases of SBL there
is no conclusive evidence that the virus is the causative agent of the
tumours. Attempts to prepare labeled cDNA from SBL-H-12578 RNA have so far
failed due to the poor virus production of the cells. Hybridization
experiments with DNA from tumour material of sporadic cases and normal
tissues have not yet been performed. Therefore the main question as to
whether the particles are of exogenous or endogenous origin remains
unanswered.
|
|---|
| Cell lines |
CVCL_6D40; SBL-H12578 |
|---|
