| Publication number |
CLPUB00235 |
|---|
| Authors |
Polianova M.T., Ivanov I.G., Jordanova P.K., Argirova R.M., Todorov T.G. |
|---|
| Title |
Permanent cell line established from rat tumour cells transformed in vivo by SR-RSV. |
|---|
| Citation |
Gen. Comp. Pathol. 28:31-40(1991) |
|---|
| Abstract |
A cell line from RSV virus-induced rat tumour, strain Schmidt-Ruppin
(SR-RSV) was established. The line consists of two morphologically different
types of cells -round or polygonal- with strongly expressed growth
properties. The time for duplication of the cell population is about 48 h.
The cells proliferate in a medium with low concentration of normal bovine
serum. The line exibits an abnormal karyotype - more of the cells possess
hypotetraploidal number of chromosomes as well as one marker chromosome.
The above-mentioned line is not virus producing siniilary to other virus-
transformed mammalian cell lines. However, when inoculated in vivo the
cells of the line induce tumour growth in chicken.
|
|---|
| Cell lines |
CVCL_0J67; LSR-SF (SR) |
|---|
