| Publication number |
CLPUB00229 |
|---|
| Authors |
Nitta M., Iida S., Komatsu H., Maeda H., Banno S., Wakita A., Iwaki O., Takeuchi G., Takada K., Mitomo Y., Yamamoto M., Koike K., Ueda R., Shamoto M. |
|---|
| Title |
A novel cell line of acute lymphoblastic leukemia (ALL-L3, Burkitt's type), NCU-L-3. |
|---|
| Citation |
Nagoya Med. J. 37:101-109(1992) |
|---|
| Web pages |
https://ci.nii.ac.jp/naid/110000023730/en |
|---|
| Abstract |
A new human cell line, NCU-L-3, is established from the peripheral blood
of a patient with acute lymphoblastic leukemia, FAB type L3. The cell line
grows in a single-cell suspension with a dobuling time of 30 to 46 hours,
and expresses L3 morphologic features. Immunologic study reveals that
NCU-L-3 cells express IgM and IgA-kappa on their surface, and react with
monoclonal antibodies to B-cell antigens. These cells are negative for
T-cell and myeloid/monocyte antigens as well as Epstein-Barr virus nuclear
antigen (EBNA). Both fresh peripheral blood and NCU-L-3 cells have a t(8;14)
karyotype. This cell line should be contributive for future studies of
cell proliferation and the oncogenesis of this neoplasm.
|
|---|
| Cell lines |
CVCL_0G12; NCU-L3 |
|---|
