| Publication number |
CLPUB00202 |
|---|
| Authors |
Gateff E., Gissmann L., Shrestha R., Plus N., Pfister H., Schroder J., zur Hausen H. |
|---|
| Title |
Characterization of two tumorous blood cell lines of Drosophila melanogaster and the viruses they contain. |
|---|
| Citation |
(In) Invertebrate systems in vitro; Kurstak E., Maramorosch K., Dubendorfer A. (eds.); pp.517-533; Elsevier; Oxford (1980) |
|---|
| Abstract |
A number of recessive-lethal mutants of Drosophila melanogaster, causing
malignant growth in different tissues and cells, have been isolated
(Gateff 1978a,b,c). Among these were three mutants which develop
malignancies of the larval hematopoietic system. The mutant larvae are
characterized by extremely enlarged, hematopoietic organs and an enormous
increase of free blood cells in the hemolymph. The increased numbers of
free blood cells in the mutant larvae facilitated the establishment of
tumorous blood cell lines in vitro from two of the three mutants. This
paper describes the growth pattern, cell morphology and fine structure of
two tumorous blood cell lines in vitro and the viruses they contain.
|
|---|
| Cell lines |
CVCL_Z706; mbn-2 CVCL_0A30; mbn-3 |
|---|
