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Cellosaurus T-47D/BCRP (CVCL_ZZ43)

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Cell line name T-47D/BCRP
Accession CVCL_ZZ43
Resource Identification Initiative To cite this cell line use: T-47D/BCRP (RRID:CVCL_ZZ43)
Comments Population: Caucasian.
Characteristics: Transfected with a Myc-tagged ABCG2/BCRP.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:74; ABCG2.
Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations
  • Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Arg (c.3140A>G); ClinVar=VCV000013652; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Leu194Phe (c.580C>T); ClinVar=VCV000127817; Zygosity=Homozygous (from parent cell line).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0553 (T-47D)
Sex of cell Female
Age at sampling 54Y
Category Cancer cell line
Publications

PubMed=15695404
Yasuo Imai, Etsuko Ishikawa, Sakiyo Asada, Yoshikazu Sugimoto;
Estrogen-mediated post transcriptional down-regulation of breast cancer resistance protein/ABCG2.
Cancer Res. 65:596-604(2005)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZZ43
Encyclopedic resources Wikidata; Q102114958
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number8