Cellosaurus cell line SW620/AD300 (CVCL

Cellosaurus SW620/AD300 (CVCL_ZZ39)

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Cell line name

SW620/AD300

Synonyms

SW620/AD-300; SW620/Ad300; SW620 Ad300; Ad300

Accession

CVCL_ZZ39

Resource Identification Initiative

To cite this cell line use: SW620/AD300 (RRID:CVCL_ZZ39)

Comments

Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_28748; Doxorubicin (Adriablastin; Adriamycin).
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.

Sequence variations

Mutation; HGNC; HGNC:583; APC; Simple; p.Gln1338Ter (c.4012C>T); ClinVar=VCV000000801; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Val (c.35G>T); ClinVar=VCV000012583; Zygosity=Homozygous (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Heterozygous (from parent cell line).
Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro309Ser (c.925C>T); ClinVar=VCV000458575; Zygosity=Heterozygous (from parent cell line).

Disease

Colon adenocarcinoma (NCIt: C4349)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Parent: CVCL_0547 (SW620)
Children:

CVCL_B6Y0 (SW620/Ad300-ABCB1ko)

Sex of cell

Male

Age at sampling

51Y