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Cellosaurus Hep-2017 (CVCL_ZY42)

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Cell line name Hep-2017
Synonyms Hep2017
Accession CVCL_ZY42
Resource Identification Initiative To cite this cell line use: Hep-2017 (RRID:CVCL_ZY42)
Comments Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1582; CCND1.
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:1773; CDK4 (Note=With p.Arg24Cys).
Genetic integration: Method=Transduction; Gene=HGNC; HGNC:11730; TERT.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Disease Glycogen storage disease type Ib (NCIt: C122661)
Glycogen storage disease due to glucose-6-phosphatase deficiency type Ib (ORDO: Orphanet_79259)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 1Y3M
Category Telomerase immortalized cell line
Publications

PubMed=33060611; DOI=10.1038/s41598-020-73992-3; PMCID=PMC7567112
Manami Nishiwaki, Masashi Toyoda, Yoshie Oishi, Seiichi Ishida, Shin-ichiro Horiuchi, Hatsune Makino-Itou, Tohru Kimura, Shin-ichi Ohno, Takashi Ohkura, Shin Enosawa, Hidenori Akutsu ...Show all 15 authors... , Atsuko Nakazawa, Mureo Kasahara, Tohru Kiyono, Akihiro Umezawa; Show fewer authors
Immortalization of human hepatocytes from biliary atresia with CDK4(R24C), cyclin D1, and TERT for cytochrome P450 induction testing.
Sci. Rep. 10:17503.1-17503.13(2020)

Cross-references
Encyclopedic resources Wikidata; Q102114116
Entry history
Entry creation29-Oct-2020
Last entry update19-Dec-2024
Version number7