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Cellosaurus SW1990-GZ (CVCL_ZW95)

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Cell line name SW1990-GZ
Synonyms SW1990/gemcitabine; SW1990-gemcitabine
Accession CVCL_ZW95
Resource Identification Initiative To cite this cell line use: SW1990-GZ (RRID:CVCL_ZW95)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_175901; Gemcitabine (Gemzar).
Derived from site: Metastatic; Spleen; UBERON=UBERON_0002106.
Cell type: Epithelial cell of pancreas; CL=CL_0000083.
Sequence variations
  • Mutation; HGNC; HGNC:27310; FLCN; Simple; p.Gln533Ter (c.1597C>T); ClinVar=VCV000096480; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Pro191del (c.569_571CTC[1]) (c.572_574delCTC); ClinVar=VCV000458551; Zygosity=Heterozygous (from parent cell line).
Disease Pancreatic adenocarcinoma (NCIt: C8294)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1723 (SW1990)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
Publications

PubMed=31452783; DOI=10.3892/ol.2019.10627; PMCID=PMC6676397
Yue Yu, Fei Ding, Meng Gao, Yi-Fu Jia, Le Ren;
Establishment and characterization of the gemcitabine-resistant human pancreatic cancer cell line SW1990/gemcitabine.
Oncol. Lett. 18:3065-3071(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZW95
Encyclopedic resources Wikidata; Q102114953
Entry history
Entry creation29-Oct-2020
Last entry update14-Aug-2025
Version number8