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Cellosaurus XPCS1RO hTERT (CVCL_ZV78)

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Cell line name XPCS1RO hTERT
Accession CVCL_ZV78
Resource Identification Initiative To cite this cell line use: XPCS1RO hTERT (RRID:CVCL_ZV78)
Comments Population: Caucasian; Moroccan.
Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:11730; TERT.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
  • Mutation; HGNC; HGNC:3437; ERCC5; Simple; p.Gly926Profs (c.2775delT) (2972delT); ClinVar=VCV000016568; Zygosity=Unspecified (from parent cell line).
Disease Xeroderma pigmentosum-Cockayne syndrome complex (NCIt: C156031)
Xeroderma pigmentosum-Cockayne syndrome complex (ORDO: Orphanet_220295)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_ZP68 (XPCS1RO)
Sex of cell Male
Age at sampling 7M
Category Telomerase immortalized cell line
Publications

PubMed=30165384; DOI=10.1093/nar/gky774; PMCID=PMC6182131
Mariangela Sabatella, Arjan F. Theil, Cristina Ribeiro-Silva, Jana Slyskova, Karen Thijssen, Chantal Voskamp, Hannes Lans, Wim Vermeulen;
Repair protein persistence at DNA lesions characterizes XPF defect with Cockayne syndrome features.
Nucleic Acids Res. 46:9563-9577(2018)

Cross-references
Encyclopedic resources Wikidata; Q98136286
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number9