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Cellosaurus UCD65 (CVCL_ZV44)

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Cell line name UCD65
Accession CVCL_ZV44
Resource Identification Initiative To cite this cell line use: UCD65 (RRID:CVCL_ZV44)
Comments Characteristics: Established from a patient-derived xenograft.
Characteristics: ER/PR-positive and ERBB2-negative.
Doubling time: 132.8 hours, 109.3 hours (Note=With 17-beta-estradiol) (PubMed=32576280).
Omics: Transcriptomics; RNAseq.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
  • Mutation; HGNC; HGNC:7765; NF1; Simple; p.Leu792fs*2 (c.2372dupT); Zygosity=Unspecified (PubMed=32576280).
  • Mutation; HGNC; HGNC:7882; NOTCH2; Simple; p.Leu2135Glufs*2 (c.6403_6404delCT); ClinVar=VCV000946387; Zygosity=Unspecified (PubMed=32576280).
Disease Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 47Y
Category Cancer cell line
Publications

PubMed=32576280; DOI=10.1186/s13058-020-01300-y; PMCID=PMC7310532
Jessica Finlay-Schultz, Britta M. Jacobsen, Duncan Riley, Kiran V. Paul, Scott Turner, Andrea Ferreira-Gonzalez, J. Chuck Harrell, Peter Kabos, Carol A. Sartorius;
New generation breast cancer cell lines developed from patient-derived xenografts.
Breast Cancer Res. 22:68.1-68.12(2020)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZV44
Encyclopedic resources Wikidata; Q98133840
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number10