Cellosaurus cell line UCD12 (CVCL

Cross-references
Cell line name	UCD12
Accession	CVCL_ZV42
Resource Identification Initiative	To cite this cell line use: UCD12 (RRID:CVCL_ZV42)
Comments	Characteristics: Established from a patient-derived xenograft. Characteristics: ER-positive, PR-negative and ERBB2-negative. Doubling time: 110.1 hours, 94.6 hours (Note=With 17-beta-estradiol) (PubMed=32576280). Omics: Transcriptomics; RNAseq. Derived from site: In situ; Breast; UBERON=UBERON_0000310.
Sequence variations	Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Ala1648Glufs*22 (c.4943delC); ClinVar=VCV001458405; Zygosity=Unspecified (PubMed=32576280). Mutation; HGNC; HGNC:8975; PIK3CA; Simple; p.His1047Leu (c.3140A>T); ClinVar=VCV000013653; Zygosity=Unspecified (PubMed=32576280).
Disease	Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	54Y
Category	Cancer cell line
Publications	PubMed=32576280; DOI=10.1186/s13058-020-01300-y; PMCID=PMC7310532 Jessica Finlay-Schultz, Britta M. Jacobsen, Duncan Riley, Kiran V. Paul, Scott Turner, Andrea Ferreira-Gonzalez, J. Chuck Harrell, Peter Kabos, Carol A. Sartorius; New generation breast cancer cell lines developed from patient-derived xenografts. Breast Cancer Res. 22:68.1-68.12(2020)
Cell line databases/resources	cancercelllines; CVCL_ZV42
Encyclopedic resources	Wikidata; Q98133836
Entry history
Entry creation	02-Jul-2020
Last entry update	10-Apr-2025
Version number	10