Cellosaurus cell line UCD4 (CVCL

Cross-references
Cell line name	UCD4
Accession	CVCL_ZV41
Resource Identification Initiative	To cite this cell line use: UCD4 (RRID:CVCL_ZV41)
Comments	Characteristics: Established from a patient-derived xenograft. Characteristics: ER/PR-positive and ERBB2-negative. Doubling time: 95.9 hours, 89.3 hours (Note=With 17-beta-estradiol) (PubMed=32576280). Omics: Transcriptomics; RNAseq. Derived from site: Metastatic; Pleural effusion; UBERON=UBERON_0000175.
Sequence variations	Mutation; HGNC; HGNC:1101; BRCA2; Simple; p.Lys585Asnfs*3 (c.1755_1759delGAAAA); ClinVar=VCV000037754; Zygosity=Unspecified (PubMed=32576280). Mutation; HGNC; HGNC:3467; ESR1; Simple; p.Asp538Gly (c.1613A>G); ClinVar=VCV003764845; Zygosity=Unspecified (PubMed=32576280).
Disease	Invasive breast carcinoma of no special type (NCIt: C4194)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Female
Age at sampling	68Y
Category	Cancer cell line
Publications	PubMed=32576280; DOI=10.1186/s13058-020-01300-y; PMCID=PMC7310532 Jessica Finlay-Schultz, Britta M. Jacobsen, Duncan Riley, Kiran V. Paul, Scott Turner, Andrea Ferreira-Gonzalez, J. Chuck Harrell, Peter Kabos, Carol A. Sartorius; New generation breast cancer cell lines developed from patient-derived xenografts. Breast Cancer Res. 22:68.1-68.12(2020)
Cell line databases/resources	cancercelllines; CVCL_ZV41
Encyclopedic resources	Wikidata; Q98133838
Entry history
Entry creation	02-Jul-2020
Last entry update	27-Nov-2025
Version number	10