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Cellosaurus 85MA (CVCL_ZU34)

[Text version]
Cell line name 85MA
Synonyms 85 MAnchester
Accession CVCL_ZU34
Resource Identification Initiative To cite this cell line use: 85MA (RRID:CVCL_ZU34)
Comments Senescence: Senesces at 36 PDL (PubMed=9649131).
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 28Y
Category Finite cell line
Publications

PubMed=8794843; DOI=10.1080/095530096145139
Sproston A.R.M., Boyle J.M., Heighway J., Birch J.M., Scott D.
Fibroblasts from Li-Fraumeni patients are resistant to low dose-rate irradiation.
Int. J. Radiat. Biol. 70:145-150(1996)

PubMed=9018113; DOI=10.1038/sj.onc.1200838
Williams K.J., Boyle J.M., Birch J.M., Norton J.D., Scott D.
Cell cycle arrest defect in Li-Fraumeni syndrome: a mechanism of cancer predisposition?
Oncogene 14:277-282(1997)

PubMed=9649131; DOI=10.1038/bjc.1998.364; PMCID=PMC2150396
Boyle J.M., Mitchell E.L.D., Greaves M.J., Roberts S.A., Tricker K., Burt E., Varley J.M., Birch J.M., Scott D.
Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families.
Br. J. Cancer 77:2181-2192(1998)

PubMed=9681890; DOI=10.1016/S0167-8140(97)00200-4
Zhou P.-K., Sproston A.R.M., Marples B., West C.M.L., Margison G.P., Hendry J.H.
The radiosensitivity of human fibroblast cell lines correlates with residual levels of DNA double-strand breaks.
Radiother. Oncol. 47:271-276(1998)

PubMed=18079351; DOI=10.1259/bjr/27072321
Arlett C.F., Green M.H.L., Rogers P.B., Lehmann A.R., Plowman P.N.
Minimal ionizing radiation sensitivity in a large cohort of xeroderma pigmentosum fibroblasts.
Br. J. Radiol. 81:51-58(2008)

Cross-references
Encyclopedic resources Wikidata; Q98125434
Entry history
Entry creation02-Jul-2020
Last entry update30-Jan-2024
Version number7