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Cellosaurus 136MA (CVCL_ZU09)

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Cell line name 136MA
Synonyms 136 MAnchester
Accession CVCL_ZU09
Resource Identification Initiative To cite this cell line use: 136MA (RRID:CVCL_ZU09)
Comments Senescence: Senesces at 24 PDL (PubMed=9649131).
Donor information: Established from an unaffected member of a Li-Fraumeni syndrome family.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 77Y
Category Finite cell line
Publications

PubMed=9018113; DOI=10.1038/sj.onc.1200838
Kaye J. Williams, John Michael Boyle, Jillian M. Birch, John D. Norton, David Scott;
Cell cycle arrest defect in Li-Fraumeni syndrome: a mechanism of cancer predisposition?
Oncogene 14:277-282(1997)

PubMed=9649131; DOI=10.1038/bjc.1998.364; PMCID=PMC2150396
John Michael Boyle, Erika L.D. Mitchell, Martin J. Greaves, Stephen A. Roberts, Katy Tricker, Emma Burt, Jennifer M. Varley, Jillian M. Birch, David Scott;
Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families.
Br. J. Cancer 77:2181-2192(1998)

Cross-references
Encyclopedic resources Wikidata; Q98125099
Entry history
Entry creation02-Jul-2020
Last entry update29-Jun-2023
Version number6