Cellosaurus cell line 2800T (CVCL

Cross-references
Cell line name	2800T
Accession	CVCL_ZT97
Resource Identification Initiative	To cite this cell line use: 2800T (RRID:CVCL_ZT97)
Comments	Derived from site: In situ; Skin; UBERON=UBERON_0002097. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr234Cys (c.701A>G); ClinVar=VCV000127820; Zygosity=Heterozygous (PubMed=7779715).
Disease	Li-Fraumeni syndrome (NCIt: C3476) Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	71Y
Category	Finite cell line
Publications	PubMed=7779715; DOI=10.1038/bjc.1995.237; PMCID=PMC2033854 Razmik Mirzayans, Remy A. Aubin, Whynn Bosnich, William A. Blattner, Malcolm C. Paterson; Abnormal pattern of post-gamma-ray DNA replication in radioresistant fibroblast strains from affected members of a cancer-prone family with Li-Fraumeni syndrome. Br. J. Cancer 71:1221-1230(1995) PubMed=9649131; DOI=10.1038/bjc.1998.364; PMCID=PMC2150396 John Michael Boyle, Erika L.D. Mitchell, Martin J. Greaves, Stephen A. Roberts, Katy Tricker, Emma Burt, Jennifer M. Varley, Jillian M. Birch, David Scott; Chromosome instability is a predominant trait of fibroblasts from Li-Fraumeni families. Br. J. Cancer 77:2181-2192(1998)
Encyclopedic resources	Wikidata; Q98125371
Entry history
Entry creation	02-Jul-2020
Last entry update	19-Dec-2024
Version number	7