Cellosaurus cell line 1873T (CVCL

Cross-references
Cell line name	1873T
Accession	CVCL_ZT93
Resource Identification Initiative	To cite this cell line use: 1873T (RRID:CVCL_ZT93)
Comments	Derived from site: In situ; Skin, dermis; UBERON=UBERON_0002067. Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Gly245Asp (c.734G>A); ClinVar=VCV000012355; Zygosity=Heterozygous (PubMed=7779715).
Disease	Li-Fraumeni syndrome (NCIt: C3476) Li-Fraumeni syndrome (ORDO: Orphanet_524)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell	Male
Age at sampling	35Y
Category	Finite cell line
Publications	PubMed=7779715; DOI=10.1038/bjc.1995.237; PMCID=PMC2033854 Razmik Mirzayans, Remy A. Aubin, Whynn Bosnich, William A. Blattner, Malcolm C. Paterson; Abnormal pattern of post-gamma-ray DNA replication in radioresistant fibroblast strains from affected members of a cancer-prone family with Li-Fraumeni syndrome. Br. J. Cancer 71:1221-1230(1995)
Encyclopedic resources	Wikidata; Q98125311
Entry history
Entry creation	02-Jul-2020
Last entry update	19-Dec-2024
Version number	7