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Cellosaurus AT5BR LCL (CVCL_ZT24)

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Cell line name AT5BR LCL
Synonyms Ataxia Telangiectasia 5 BRighton LCL; LB433; 433
Accession CVCL_ZT24
Resource Identification Initiative To cite this cell line use: AT5BR LCL (RRID:CVCL_ZT24)
Comments Transformant: NCBI_TaxID; 10376; Epstein-Barr virus (EBV).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Mutation; HGNC; HGNC:795; ATM; Simple; p.Arg1921Ter (c.5763-1050A>G) (IVS40+1126A>G) (5762ins137); ClinVar=VCV000003021; Zygosity=Unspecified (from autologous cell line AT5BR).
Disease Ataxia telangiectasia syndrome (NCIt: C2887)
Ataxia telangiectasia (ORDO: Orphanet_100)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_WX71 ! AT5BR
Sex of cell Female
Age at sampling 30Y
Category Transformed cell line
Publications

PubMed=7836839; DOI=10.1080/09553009414551951
Jane Cole, Colin Francis Arlett;
Cloning efficiency and spontaneous mutant frequency in circulating T-lymphocytes in ataxia-telangiectasia patients.
Int. J. Radiat. Biol. 66:S123-S131(1994)

Cross-references
Encyclopedic resources Wikidata; Q98125517
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number8