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Cellosaurus XP51RO (CVCL_ZP55)

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Cell line name XP51RO
Synonyms Xeroderma Pigmentosum 51 ROtterdam; XFE
Accession CVCL_ZP55
Resource Identification Initiative To cite this cell line use: XP51RO (RRID:CVCL_ZP55)
Comments Population: Afghan.
Derived from site: In situ; Skin; UBERON=UBERON_0002097.
Cell type: Fibroblast of skin; CL=CL_0002620.
Sequence variations
Disease XFE progeroid syndrome (NCIt: C173111)
Genetic progeroid syndrome (ORDO: Orphanet_363245)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_ZP56 (XP51RO-hTERT)
Sex of cell Male
Age at sampling 15Y
Category Finite cell line
Publications

PubMed=17183314; DOI=10.1038/nature05456
Laura J. Niedernhofer, George A. Garinis, Anja Raams, Astrid S. Lalai, Andria Rasile Robinson, Esther Appeldoorn, Hanny Odijk, Roos L. Oostendorp, Anwaar Ahmad, Wibeke van Leeuwen, Arjan F. Theil ...Show all 18 authors... , Wim Vermeulen, Gijsbertus T.J. van der Horst, Peter Meinecke, Wim J. Kleijer, Jan Vijg, Nicolaas G.J. Jaspers, Jan Hendrik Jozef Hoeijmakers; Show fewer authors
A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.
Nature 444:1038-1043(2006)

PubMed=20221251; DOI=10.1371/journal.pgen.1000871; PMCID=PMC2832669
Anwaar Ahmad, Jacqueline Henriette Enzlin, Nikhil R. Bhagwat, Nils Wijgers, Anja Raams, Esther Appledoorn, Arjan F. Theil, Jan Hendrik Jozef Hoeijmakers, Wim Vermeulen, Nicolaas G.J. Jaspers, Orlando David Scharer, Laura J. Niedernhofer;
Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patients.
PLoS Genet. 6:e1000871.1-e1000871.11(2010)

Cross-references
Encyclopedic resources Wikidata; Q98135908
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number7