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Cellosaurus Tango GPCR-bla U2OS (CVCL_ZJ93)

[Text version]
Cell line name Tango GPCR-bla U2OS
Synonyms Tango GPCR U2OS
Accession CVCL_ZJ93
Resource Identification Initiative To cite this cell line use: Tango GPCR-bla U2OS (RRID:CVCL_ZJ93)
Comments Population: Caucasian.
Characteristics: This is the parental cell line for all other ThermoFisher Tango cell lines. It is not distributed.
Characteristics: Stably expresses a beta-arrestin/TEV protease fusion protein and a beta-lactamase reporter gene under the control of an upstream activator sequence (UAS).
Transfected with: HGNC; 712; ARRB2.
Transfected with: UniProtKB; P04517; Tobacco etch virus (TEV) protease (AA 2038-2279).
Transfected with: UniProtKB; P62593; Escherichia coli beta-lactamase bla (with p.Met1_Phe22del, p.Ala23Met, p.Val82Ile and p.Met184Val).
Derived from site: In situ; Bone, tibia; UBERON=UBERON_0000979.
Sequence variations
  • Mutation; HGNC; 9277; PPM1D; Simple; p.Arg458Ter (c.1372C>T); ClinVar=VCV002445214; Zygosity=Heterozygous (from parent cell line).
Disease Osteosarcoma (NCIt: C9145)
Osteosarcoma (ORDO: Orphanet_668)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0042 (U2OS)
CVCL_ZK27 (T-REx Tango GHSR-bla U2OS)CVCL_ZK28 (T-REx Tango P2RY14-bla U2OS)CVCL_ZK53 (Tango ADORA1-bla U2OS)
CVCL_ZJ94 (Tango ADORA3-bla U2OS)CVCL_ZJ95 (Tango ADRA2A-bla U2OS)CVCL_ZJ96 (Tango AGTR1-bla U2OS)
CVCL_ZJ97 (Tango AGTRL1-bla U2OS)CVCL_ZJ98 (Tango CCR1-bla U2OS)CVCL_ZJ99 (Tango CCR2-bla U2OS)
CVCL_ZK00 (Tango CCR3-bla U2OS)CVCL_ZK01 (Tango CCR4-bla U2OS)CVCL_ZK02 (Tango CCR5-bla U2OS)
CVCL_ZK03 (Tango CCR6-bla U2OS)CVCL_ZK04 (Tango CCR7-bla U2OS)CVCL_ZK05 (Tango CHRM2-bla U2OS)
CVCL_ZK06 (Tango CMKLR1-bla U2OS)CVCL_ZK07 (Tango CNR1-bla U2OS)CVCL_ZK08 (Tango CNR2-bla U2OS)
CVCL_ZK09 (Tango CXCR1-bla U2OS)CVCL_ZK10 (Tango CXCR2-bla U2OS)CVCL_ZK11 (Tango CXCR3-bla U2OS)
CVCL_ZK12 (Tango CXCR4-bla U2OS)CVCL_ZK13 (Tango CXCR6-bla U2OS)CVCL_ZK14 (Tango CXCR7-bla U2OS)
CVCL_ZK15 (Tango DRD1-bla U2OS)CVCL_ZK16 (Tango EDG1-bla U2OS)CVCL_ZK17 (Tango EDG2-bla U2OS)
CVCL_ZK18 (Tango EDG3-bla U2OS)CVCL_ZK37 (Tango EDG4-bla U2OS)CVCL_ZK38 (Tango EDG5-bla U2OS)
CVCL_ZK30 (Tango EDG6-bla U2OS)CVCL_ZK32 (Tango EDG7-bla U2OS)CVCL_ZK33 (Tango EDG8-bla U2OS)
CVCL_ZL09 (Tango F2RL1-bla U2OS)CVCL_ZL03 (Tango GALR2-bla U2OS)CVCL_ZK95 (Tango GLP2R-bla U2OS)
CVCL_ZL12 (Tango GPR1-bla U2OS)CVCL_ZL11 (Tango GPR109A-bla U2OS)CVCL_ZL13 (Tango GPR119-bla U2OS)
CVCL_ZK31 (Tango GPR120-bla U2OS)CVCL_ZK34 (Tango GPR23-bla U2OS)CVCL_ZL10 (Tango GPR35-bla U2OS)
CVCL_ZL14 (Tango GPR44 (CRTH2)-bla U2OS)CVCL_ZK29 (Tango GPR8-bla U2OS)CVCL_ZK36 (Tango GPR87-bla U2OS)
CVCL_ZK35 (Tango GPR92-bla U2OS)CVCL_ZL06 (Tango HTR1A-bla U2OS)CVCL_ZK94 (Tango HTR1D-bla U2OS)
CVCL_ZK96 (Tango HTR2A-bla U2OS)CVCL_ZL05 (Tango M1-bla U2OS)CVCL_ZL04 (Tango M4-bla U2OS)
CVCL_ZL00 (Tango MTNR1B-bla U2OS)CVCL_ZL02 (Tango NPY1R-bla U2OS)CVCL_ZK92 (Tango NPY2R-bla U2OS)
CVCL_ZL01 (Tango NPY5R-bla U2OS)CVCL_ZL07 (Tango OPRD1-bla U2OS)CVCL_ZK97 (Tango OPRK1-bla U2OS)
CVCL_ZL08 (Tango OPRL1-bla U2OS)CVCL_ZK93 (Tango OPRM1-bla U2OS)CVCL_ZK19 (Tango PTAFR-bla U2OS)
CVCL_ZK20 (Tango RLN3R1-bla U2OS)CVCL_ZK21 (Tango SSTR1-bla U2OS)CVCL_ZK22 (Tango SSTR2-bla U2OS)
CVCL_ZK23 (Tango SSTR5-bla U2OS)CVCL_ZK24 (Tango TACR1-bla U2OS)CVCL_ZK25 (Tango TACR3-bla U2OS)
CVCL_ZK26 (Tango TBXA2R-bla U2OS)
Sex of cell Female
Age at sampling 15Y
Category Cancer cell line

PubMed=19726785; DOI=10.1177/1087057109343809
Wetter J.A., Revankar C., Hanson B.J.
Utilization of the Tango beta-arrestin recruitment technology for cell-based EDG receptor assay development and interrogation.
J. Biomol. Screen. 14:1134-1141(2009)

Encyclopedic resources Wikidata; Q98133124
Entry history
Entry creation02-Jul-2020
Last entry update05-Oct-2023
Version number7