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Cellosaurus LB2077-MELC (CVCL_ZG21)

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Cell line name LB2077-MELC
Accession CVCL_ZG21
Resource Identification Initiative To cite this cell line use: LB2077-MELC (RRID:CVCL_ZG21)
Comments From: Ludwig Institute for Cancer Research, Brussels Branch; Brussels; Belgium.
Derived from site: Metastatic; Heart; UBERON=UBERON_0000948.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-146C>T (c.250C>T) (C250T); Zygosity=Unspecified; Note=In promoter (PubMed=28636941).
Disease Melanoma (NCIt: C3224)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_ZG19 ! LB2077-MELA
CVCL_ZG20 ! LB2077-MELB
Sex of cell Female
Age at sampling 24Y
Category Cancer cell line
Publications

PubMed=28636941; DOI=10.1016/j.celrep.2017.05.046
Nikenza Viceconte, Marie-Sophie Dheur, Eva Majerova, Christophe E. Pierreux, Jean-Francois Baurain, Nicolas van Baren, Anabelle Decottignies;
Highly aggressive metastatic melanoma cells unable to maintain telomere length.
Cell Rep. 19:2529-2543(2017)

Cross-references
Encyclopedic resources Wikidata; Q98126866
Entry history
Entry creation02-Jul-2020
Last entry update19-Dec-2024
Version number7