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Cellosaurus CLC46 (CVCL_ZG07)

[Text version]
Cell line name CLC46
Synonyms Chinese Liver Cancer cell line 46
Accession CVCL_ZG07
Resource Identification Initiative To cite this cell line use: CLC46 (RRID:CVCL_ZG07)
Comments Part of: Liver Cancer Model Repository (LIMORE).
Population: Chinese.
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Omics: Genome sequenced.
Omics: Transcriptome analysis by RNAseq.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; 11110; ARID1A; Simple; p.Ser1990Cysfs*5 (c.5968_5978delAGCCTGTCATT); Zygosity=Unspecified (PubMed=31378681).
  • Mutation; HGNC; 11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=31378681).
  • Mutation; HGNC; 11998; TP53; Simple; p.Ser315Leufs*30 (c.943delT); Zygosity=Unspecified (PubMed=31378681).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): PubMed=31378681

Markers:
AmelogeninX,Y
CSF1PO10,11
D5S8189,12
D7S82012
D13S3179,10
D16S53911,13
TH019
TPOX8,11
vWA14,17

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Publications

PubMed=31378681; DOI=10.1016/j.ccell.2019.07.001
Qiu Z.-X., Li H., Zhang Z.-T., Zhu Z.-F., He S., Wang X.-J., Wang P.-C., Qin J.-J., Zhuang L.-P., Wang W., Xie F.-B., Gu Y., Zou K.-K., Li C., Li C., Wang C.-H., Cen J., Chen X.-T., Shu Y.-J., Zhang Z., Sun L.-L., Min L.-H., Fu Y., Huang X.-W., Lv H., Zhou H., Ji Y., Zhang Z.-G., Meng Z.-Q., Shi X.-L., Zhang H.-B., Li Y.-X., Hui L.-J.
A pharmacogenomic landscape in human liver cancers.
Cancer Cell 36:179-193.e11(2019)

Cross-references
Cell line databases/resources LIMORE; CLC46
Encyclopedic resources Wikidata; Q98125675
Gene expression databases GEO; GSM3394801
Entry history
Entry creation02-Jul-2020
Last entry update29-Jun-2023
Version number7