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Cellosaurus CLC3 (CVCL_ZF90)

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Cell line name CLC3
Synonyms Chinese Liver Cancer cell line 3
Accession CVCL_ZF90
Resource Identification Initiative To cite this cell line use: CLC3 (RRID:CVCL_ZF90)
Comments Part of: Liver Cancer Model Repository (LIMORE).
Population: Chinese.
Doubling time: 17.72 hours (PubMed=31378681).
Omics: Genomics; Whole genome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:583; APC; Simple; p.Pro865Glnfs*50 (c.2594_2597delCAGC); Zygosity=Unspecified (PubMed=31378681).
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=31378681).
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg280Ile (c.839G>T); ClinVar=VCV000161517; Zygosity=Unspecified (PubMed=31378681).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Age at sampling 77Y
Category Cancer cell line
STR profile Source(s): PubMed=31378681

Markers:
AmelogeninX
CSF1PO10,11
D5S8189,10
D7S82011
D13S31712
D16S53912
TH019
TPOX8,11
vWA16,18

Run an STR similarity search on this cell line
Web pages Provider; BRICS; BRICS0013; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3828
Publications

PubMed=31378681; DOI=10.1016/j.ccell.2019.07.001; PMCID=PMC7505724
Zhi-Xin Qiu, Hong Li, Zheng-Tao Zhang, Zhen-Feng Zhu, Sheng He, Xu-Jun Wang, Peng-Cheng Wang, Jian-Jie Qin, Li-Ping Zhuang, Wei Wang, Fu-Bo Xie ...Show all 33 authors... , Ying Gu, Ke-Ke Zou, Chao Li, Chun Li, Chen-Hua Wang, Jin Cen, Xiao-Tao Chen, Ya-Jing Shu, Zhao Zhang, Lu-Lu Sun, Li-Hua Min, Yong Fu, Xiao-Wu Huang, Hui Lv, He Zhou, Yuan Ji, Zhi-Gang Zhang, Zhi-Qiang Meng, Xiao-Lei Shi, Hai-Bin Zhang, Yi-Xue Li, Li-Jian Hui; Show fewer authors
A pharmacogenomic landscape in human liver cancers.
Cancer Cell 36:179-193.e11(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_ZF90
LIMORE; CLC3
Encyclopedic resources Wikidata; Q98125652
Gene expression databases GEO; GSM2551559
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number11