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Cellosaurus CLC28 (CVCL_ZF88)

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Cell line name CLC28
Synonyms Chinese Liver Cancer cell line 28
Accession CVCL_ZF88
Resource Identification Initiative To cite this cell line use: CLC28 (RRID:CVCL_ZF88)
Comments Part of: Liver Cancer Model Repository (LIMORE).
Population: Chinese.
Doubling time: 35.3 hours (PubMed=31378681).
Transformant: NCBI_TaxID; 10407; Hepatitis B virus (HBV).
Omics: Genomics; Whole genome sequencing.
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:11730; TERT; Simple; c.1-124C>T (c.228C>T) (C228T); Zygosity=Unspecified; Note=In promoter (PubMed=31378681).
Disease Adult hepatocellular carcinoma (NCIt: C7956)
Adult hepatocellular carcinoma (ORDO: Orphanet_210159)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 59Y
Category Cancer cell line
STR profile Source(s): PubMed=31378681

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,12
D7S82011
D13S31710,12
D16S53910,11
TH017,8
TPOX8,9
vWA17

Run an STR similarity search on this cell line
Web pages Provider; BRICS; BRICS0051; http://www.brics.ac.cn/cell/template/cell/cell_detail.html?id=3866
Publications

PubMed=31378681; DOI=10.1016/j.ccell.2019.07.001; PMCID=PMC7505724
Zhi-Xin Qiu, Hong Li, Zheng-Tao Zhang, Zhen-Feng Zhu, Sheng He, Xu-Jun Wang, Peng-Cheng Wang, Jian-Jie Qin, Li-Ping Zhuang, Wei Wang, Fu-Bo Xie ...Show all 33 authors... , Ying Gu, Ke-Ke Zou, Chao Li, Chun Li, Chen-Hua Wang, Jin Cen, Xiao-Tao Chen, Ya-Jing Shu, Zhao Zhang, Lu-Lu Sun, Li-Hua Min, Yong Fu, Xiao-Wu Huang, Hui Lv, He Zhou, Yuan Ji, Zhi-Gang Zhang, Zhi-Qiang Meng, Xiao-Lei Shi, Hai-Bin Zhang, Yi-Xue Li, Li-Jian Hui; Show fewer authors
A pharmacogenomic landscape in human liver cancers.
Cancer Cell 36:179-193.e11(2019)

Cross-references
Cell line databases/resources LIMORE; CLC28
Encyclopedic resources Wikidata; Q98125650
Gene expression databases GEO; GSM2551557
Entry history
Entry creation02-Jul-2020
Last entry update10-Apr-2025
Version number9