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Cellosaurus NKc21 (CVCL_ZE33)

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Cell line name NKc21
Accession CVCL_ZE33
Resource Identification Initiative To cite this cell line use: NKc21 (RRID:CVCL_ZE33)
Comments Genetic integration: Method=Transduction; Gene=UniProtKB; P03126; Human papillomavirus type 16 protein E6.
Genetic integration: Method=Transduction; Gene=UniProtKB; P03129; Human papillomavirus type 16 protein E7.
Genetic integration: Method=Transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Sex unspecified
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=20977447; DOI=10.1111/j.1365-2133.2010.10092.x
Jean Christopher Chamcheu, Inger Pihl-Lundin, Cedrique Eteti Mouyobo, Therese Gester, Marie Virtanen, Aristidis Moustakas, Harshad Ambaram Navsaria, Anders Vahlquist, Hans Torma;
Immortalized keratinocytes derived from patients with epidermolytic ichthyosis reproduce the disease phenotype: a useful in vitro model for testing new treatments.
Br. J. Dermatol. 164:263-272(2011)

PubMed=28765827; DOI=10.1016/j.omtm.2017.06.008; PMCID=PMC5527154
Magomet Aushev, Ulrich Koller, Claudio Mussolino, Toni Cathomen, Julia Reichelt;
Traceless targeting and isolation of gene-edited immortalized keratinocytes from epidermolysis bullosa simplex patients.
Mol. Ther. Methods Clin. Dev. 6:112-123(2017)

Cross-references
Encyclopedic resources Wikidata; Q98127919
Entry history
Entry creation02-Jul-2020
Last entry update14-Aug-2025
Version number9