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Cellosaurus IPAM 3D4/21/CD163 (CVCL_ZE11)

[Text version]
Cell line name IPAM 3D4/21/CD163
Synonyms 3D4/21/CD163
Accession CVCL_ZE11
Resource Identification Initiative To cite this cell line use: IPAM 3D4/21/CD163 (RRID:CVCL_ZE11)
Comments Virology: Highly susceptible to infection by porcine reproductive and respiratory syndrome virus type 2 (PRRSV-2) (PubMed=31493424).
Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Genetic integration: Method=Transfection; Gene=VGNC; VGNC:112737; Pig CD163.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pSV3-neo).
Derived from site: In situ; Lung, alveolus; UBERON=UBERON_0002299.
Cell type: Alveolar macrophage; CL=CL_0000583.
Species of origin Sus scrofa (Pig) (NCBI Taxonomy: 9823)
Breed/subspecies: Landrace; VBO=VBO_0001161.
Hierarchy Parent: CVCL_0F14 (IPAM 3D4/21)
Sex of cell Sex unspecified
Age at sampling 12W
Category Transformed cell line
Publications

PubMed=31493424; DOI=10.1016/j.jviromet.2019.113727
Xiang-Peng Wang, Guan-Yu Wang, Ning Wang, Jia Liu, Yu-Qing Cai, Mei-Jiao Ren, Zhi-Jun Li;
A simple and efficient method for the generation of a porcine alveolar macrophage cell line for high-efficiency porcine reproductive and respiratory syndrome virus 2 infection.
J. Virol. Methods 274:113727.1-113727.7(2019)

Cross-references
Encyclopedic resources Wikidata; Q98125390
Entry history
Entry creation02-Jul-2020
Last entry update14-Aug-2025
Version number13