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Cellosaurus 293T ERR reporter (CVCL_ZD87)

[Text version]
Cell line name 293T ERR reporter
Synonyms ERRalpha Expressing HEK-293T/17 Cell Line; ERR reporter
Accession CVCL_ZD87
Resource Identification Initiative To cite this cell line use: 293T ERR reporter (RRID:CVCL_ZD87)
Comments Characteristics: Expresses a construct with a pleiotropic nuclear receptor enhancer MHRE that controls the expression of GFP and luciferase (AAB-GFP-Luc).
Genetic integration: Method=Transfection; Gene=FPbase; R9NL8; eGFP (Note=Enhanced GFP).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P08659; Photinus pyralis firefly-type luciferase.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P13249; Streptomyces alboniger pac (PuroR).
Transformant: NCBI_TaxID; 28285; Human adenovirus C serotype 5.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=tsA).
Derived from site: In situ; Fetal kidney; UBERON=UBERON_0002113.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1926 (HEK293T/17)
Sex of cell Female
Age at sampling Fetus
Category Transformed cell line
Publications

PubMed=28346099; DOI=10.1177/2472555216689772; PMCID=PMC5486949
Christina T. Teng, Jui-Hua Hsieh, Jing-Hua Zhao, Rui-Li Huang, Meng-Hang Xia, Negin Martin, Xiao-Hua Gao, Darlene Dixon, Scott S. Auerbach, Kristine L. Witt, Bruce Alex Merrick;
Development of novel cell lines for high-throughput screening to detect estrogen-related receptor alpha modulators.
SLAS Discov. 22:720-731(2017)

Cross-references
Cell line collections (Providers) Kerafast; ENH070-FP
Encyclopedic resources Wikidata; Q98125374
Entry history
Entry creation02-Jul-2020
Last entry update14-Aug-2025
Version number9