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Cellosaurus MEF Actbf/f-Actg1f/f (CVCL_ZD80)

[Text version]
Cell line name MEF Actbf/f-Actg1f/f
Synonyms Floxed Beta-Actin (Actb)/Gamma-Actin (Actg1) Double KO MEF Cell Line; Actb LL Actg1 LL-Large T
Accession CVCL_ZD80
Resource Identification Initiative To cite this cell line use: MEF Actbf/f-Actg1f/f (RRID:CVCL_ZD80)
Comments Characteristics: Actb and Actg1 can be both knocked-out after exogenous expression of Cre recombinase via Cre-Lox recombination.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Embryo; UBERON=UBERON_0000922.
Cell type: Fibroblast; CL=CL_0000057.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Sex of cell Sex unspecified
Age at sampling 13-14FD
Category Transformed cell line
Publications

PubMed=28077619; DOI=10.1091/mbc.E16-07-0503; PMCID=PMC5349784
Patrinostro X.-B., O'Rourke A.R., Chamberlain C.M., Moriarity B.S., Perrin B.J., Ervasti J.M.
Relative importance of betacyto- and gammacyto-actin in primary mouse embryonic fibroblasts.
Mol. Biol. Cell 28:771-782(2017)

Cross-references
Cell line collections (Providers) Kerafast; EMN020-FP
Encyclopedic resources Wikidata; Q98127204
Entry history
Entry creation02-Jul-2020
Last entry update29-Jun-2023
Version number5